Sinemet half life

Common Questions and Answers about Sinemet half life

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Avatar n tn 5-6 years ago, she started parkinson treatment as 3 per day 25/100 sinemet. Half year ago, her motion slows down, drooling a lot. Sinemet was increased to 3 per day 25/250. it really helped at first. 2 months later, dyskinesia occurred in tongue/jaw, drooling returned. Sinemet dosage then was decreased to 2 per day 25/250 (9am, 2pm), Requip 0.125 (9pm). Dyskinesia improved. 1.5 month ago, teeth grinding started day and night.
Avatar n tn My father has had RLS for years and taking Sinemet to control it. Lately he has been acting differently almost like he has no control over his arms, mouth and legs. Can taking Sinemet for a long period of time cause Parkinson or similar disorders?
Avatar m tn I started taking Sinemet about 3 months ago and my blood sugar levels, insulin resistance are all over the map. In the morning I fight to get my BSs down and now, in the afternoon, I often have BS crashes into severe hypo territory. I've been to the emergency twice these past two weeks - a week ago Friday with hyper, ketones and this last Friday with a severe hypo with 5 units still active!!!
Avatar f tn The half-life of a drug is how long it takes for half of it to be eliminated from the bloodstream. Hope that helps.
6298176 tn?1380134459 It has a very long half life, though I can't give you specifics. The dose and how long you were on it does factor in. Your doctor should be able to help you with your questions on this.
Avatar f tn I hated that because it worked so well, but side effects were intolerable. This as of April 28th. Was started on Sinemet. Was told this does not work as well as Requip, but was less likely to have same side effects. Said he could add darvocet if necesary.Also take ativan 1mg 3 x daily since the brain surgery, and 1-2 at night for help with sleep. Every other sleep aid made above symptoms worse. Did tapered Requip withdrawal while adding the sinemet.
Avatar f tn I hated that because it worked so well. This as of April 28th. Was started on Sinemet. Was told this does not work as well as Requip, but was less likely to have same side effects. Said he could add darvocet if necesary.Also take ativan 1mg 3 x daily since brain surgery, and 1-2 at night for help with sleep. Every other sleep aid made morning "miseries"symptoms worse. Tapered Requip withdrawal while adding Sinemet. Right now taking 1/2 afternoon and 1 at night.
Avatar f tn In 2001, following a sleep study, I was found to have restless leg syndrom and prescribed Sinemet for the symptoms. Over the years the symptoms increased, and I now have severe lower back and neck pain, joint pain (especially knees) and my RLS has become more pronounced. I now have the symptoms beginning much earlier in the day, so have had to increase the use of Sinemet.
2080475 tn?1332126191 decided to quit taking it on a monday felt fine all week untill sun when i went into serious withdrawl! so as far as half life im not sure? but you can bet i was back on it mon! so i guess it was in my system for 6 days after i stopped. p.s.
Avatar f tn ?? Does anyone know the Half life of SUBOXONE - Beprenorphine.? I HEARD it was 70 hours, but that's what I heard....unsure if that is even accurate?
535882 tn?1396576685 whats the half life for syntriod. about how much time does it take to build up in you and also leave your system?
1168317 tn?1330262837 he also said that he wants to trial me on a drug called SINEMET that might help my tremors and stiffness . he said its used for parkinsons but you DO NOT have that but i just thinks it might help with your symptoms. cos at the end of the day anything that helps your symptoms is better for you long term ??. so as you can imagine im very confused as to what the hell is going on !!!
Avatar f tn My doctor prescribed Sinemet (generic name: carbadopa/levo) 25/100mg each night, and I no longer have restless legs. I've been taking it for about 4 years now, and as far as I know, I don't have any negative side effects from it. (I know you said you prefer to balance yourself without pharmaceuticals, but if you don't find a way to do that, the Sinemet really works for me.) Sleep is SO important.
Avatar f tn I too have been on both of these meds and have had similar issues. Have you been on Sinemet yet? Requip and Mirapex are dopamine agonists, but Sinemet is a dopamine replacement and is best reserved for when the agonists no longer work. SinemetCR worked for me for a few years before the side effects outweighed the decreasing benefits. It's more complicated to optimize it's effectiveness, as one is best served to consider the timing, volume and content of their meals.
Avatar m tn I've been dealing with horrible spasticity since April and has gotten worse. I don't sleep much anymore at night and I work full time. My MRI shows no changes (minimal) and thoracic spine has no lesions. I've tried so many medications including sativex. I'm so tired and done with it all. I've also tried amitripyline, carbonmezipine, sinemet, quinine, nabilone and nothing. Please help....
1084115 tn?1385228589 The mean half-life for multiple doses in the body is about 12 days, but very long-term kinetics are dominated by the kinetics of RBCs (half-life 40 days). RBCs store ribavirin for the lifetime of the cells, releasing it into the body's systems when old cells are degraded in the spleen.
459155 tn?1264008142 ok plz if I am explaining this wrong (anyone feel free to correct me if I am ) The 36 hour half life mean half of the dosage is still active at 36 hours ??
738895 tn?1234654277 I think heroin has a half life of 4-8 hrs, and methadown 20-36hrs, i understand that it takes 36hrs for half the drug dose to leave your body, but theres only 2 day deference between the two drugs but methadown takes months to kick and heroin weeks. thats the part i dont understand but theres only 2 day deference between the two. anyone with knowledge please try in a laymen terms to explain. thanks for any help in advance.
Avatar n tn t know if it is from the meds... as far as the meds. Sinemet and I just quit Nuepro... This discussion is related to <a href='http://www.medhelp.org/posts/show/227738'>hard bump under left armpit</a>.
Avatar m tn Diagnosing PD is really done visually. There are no definitive tests. The MRI would have been done to rule out any other abnormal condition, i.e. a stroke. No blood test shows a PD condition. I'm 59 years old and was diagnosed two years ago. It's also a good idea to seek out a second opinion from a movement disorder specialist. I was diagnosed, sought out a second opinion, and then moved on to a movement disorder specialist.