Simvastatin and muscle pain

Common Questions and Answers about Simvastatin and muscle pain

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Avatar f tn Clinically, high levels of HMG-CoA reductase inhibitory activity in plasma may be associated with an increased risk of musculoskeletal toxicity. Myopathy manifested as muscle pain and/or weakness associated with grossly elevated creatine kinase exceeding ten times the upper limit of normal has been reported occasionally. Rhabdomyolysis has also occurred rarely, which may be accompanied by acute renal failure secondary to myoglobinuria and may result in death.
Avatar f tn make sure you do not take with grapefruit juice, report any signs and symptoms of infections, unexplained muscle pain, tenderness/weekness. i hope this helps!!! this all i know about the med.
Avatar m tn ) For the past 20 years, I have avoided NSAIDs, acetaminophens, other pain relievers and muscle relaxants because of their adverse effects to liver and kidneys (personally more significant because my dad had kidney disease). Since cannabidiol inhibits the liver's production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects.
Avatar f tn Patients were put on a cholesterol-lowering diet and given one of the medications. After 18 weeks, patients given simvastatin had significantly lower total cholesterol, lower LDL, lower triglycerides, and higher HDL cholesterol levels than those who took pravastatin. The study found that the patients on simvastatin achieved the target LDL level of less than 130, more than those on pravastatin (65 percent on simvastatin versus 35 percent on pravastatin).
Avatar f tn My endocrinologist prescribed me Atorvastatin 40mg in place of the simvastatin but it has since given my major chest pain and muscle weakness in my fingers and legs; so I was advised by the pharmacist to stop that and I have only taken the new statin twice and tonight was the second time taking it. Is simvastatin something that can be eased up to a higher dose to do the exact same thing atorvastatin does for the bad cholesterol?
Avatar n tn I have been on 20 mg of simvastatin and 3000 mg niaspan now my ck levels have went from 60 to 295 i could hardly walk .will my levels come down if i lower dose. and reverse damage. i have 12 stents .the rest of my blood work is fine.
620048 tn?1358018235 They read up on all of her meds called the Dr. he stopped the simvastatin and she is much better now and cont to improve. My husband is on it and has no problems. As with most drugs, they affect people different.
2085202 tn?1373199740 Hello all. I'm a 26 year old male and have a cholesterol problem with high tryglycerides. I understand I NEED to be on something but i've stopped taking my simvastatin as the longer i've been on it i'm noticing my arms are becoming pathetically frail , weak and tiny. My wrists seemed to have shrunk to the point of where I can cuff my hand over them to a scary point. At first I thought I had a disease of some kind but tests have shown everything is fine.
Avatar f tn There are a lot of things that could cause the abdominal pain, jaw pain, and tingling feeling and they are not listed as side effects, but they could be related. I googled Simvastatin and found that it is a cholesterol medication, Zocor (one of the statins). When I clicked on the link it immediately brought up a safety warning that said on certain high doses there is an increased risk of muscle injury.
808920 tn?1268057768 Shoulder blade popping, muscle cramping on left side of back and joint discomfort? 3. Does anyone know what a normal recovery time is for myocarditis and is the side pain and shoulder popping/muscle cramping any side effects of this illness? I would like to communicate by email or phone with others that have had myocarditis. My email is tivy1960 at charter .dot. com. if anyone would like to chat about there results and symptoms with their recovery.
Avatar n tn http://www.medicinenet.com/simvastatin/article.htm This could be an allergic reaction to the drug. It will stop if the drug is withdrawn. You need to inform your doctor about this development. He might want to substitute it with another. It cannot be a time coincidence unless you had the itching prior to starting the drug. You could apply an anti-itch lotion or cold compresses on the skin to soothe the areas.
Avatar n tn We have been on simvastatin for (wife for 1+ years, me for 2+ years) and stopped about 5-6 months ago - wife still having pains in the butt some dizziness and leg pain, but getting better - I am having butt pain and leg pains, swollen left knee, (but joint pain seems OK on stairs), recovery seems slower than my wife's. But both of us have just been diagnosed with right enlarged renal cysts which were not there before taking simvastatin.
428155 tn?1203688894 in New Zealand), which my GP had prescribed me 2 years beforehand to control my cholesterol level. I stopped simvastatin and all fibrillations have disappeared. As I was taking simvastatin, I was in fibrillation 17% of the time; 1 month after I stopped simvastatin, the level was down to 0%. I am now experimenting with alternative cholesterol control methods: Omega 3 gels, ground linseed, charcoal.
1616588 tn?1298639117 Hi there, this class of drugs (Statins) frequently deplete an enzyme in the body called Co-Enzyme Q10. Deficiency of this enzyme can cause the cramp, muscle and overall feeling of weakness. You can buy this enzyme with the supplements. It can be expensive so buy the highest strength you can afford. Have you told your doctor about this? Your doctor should rule out whether this is a more serious side effect of this class of drugs. Avoid grapefruit or grapefruit juice.
Avatar f tn The risk of any side effect is anywhere between 2% and 5% which classifies this as very safe. Common side effects are muscle pain and sore joints. I would take it and just keep an eye out for anything that may be a side effect. This link will tell you what to look for; http://www.emedicinehealth.com/drug-simvastatin/article_em.
Avatar m tn Since I have familial high blood fats, my doctor has tried me on several different types and doses of statins, and I always get fairly severe muscle pain in the shoulders and arms. This is a symptom that may occur in approximately 30% of patients on statins. Apparently, though, there may not be any REAL damage to the muscles in most cases, in spite of the intensity of the pain. There are blood tests to determine if actual muscle damage is occurring.
Avatar f tn Can medications to lower high chlorestorol damage your liver, I have non-alcoholic fatty liver disease now and I am afraid to take statin drugs. How important is my concern. Simvastatin is one in particular.
562206 tn?1216150022 I did look up some info on the statins and it is a commonly known side effect as you describe, the muscle pain back pain and leg pain. I even seen some had chest pains. I don't know what to suggest to you other than talking to your Dr about possibly going off of the medication and seeing where your at then. I know how frustrating it is to get a Dr to listen sometimes but please don't give up, there are some very good Dr;s you just have to keep going till you find one.
Avatar m tn Hi, My partner is a 35 yr old male who for the last 2 weeks has been suffering from severe muscle cramps in is right hand and right foot. It starts with a tingling in his right arm from the elbow downwards which then causes his hand to cramp and lock with the fingers clawing in towards his palm. At the same time, his leg starts to burn from the caf down into the foot and goes into a cramp with his toes turning downwards and inwards.
Avatar m tn x/full very interesting study which confirms why simvastatin, lowering cholesterol drug and actos (diabetes 2 drug), have anti hbv activity lowering hbvdna, cancer risk, all this without problems of resistance and acting on all hbv mutants conclusions: The discovery of the mechanisms by which HBV is controlled by the hepatic metabolic milieu may broaden our understanding of the unique regulation of HBV expression and may also explain the mechanisms by which HBV induces liver pathologies.
Avatar m tn Are you sure your muscle pain is related to the statin use? Muscle pains are the most common complaint and has many, many causes. In any case, there is no danger in stopping Crestor suddenly, but discuss it with your doctor. I would have a couple questions for your doctor. First off, why does he have a target of an LDL under 100? That is normally the recommendation for people at high risk of heart disease or those that already have heart disease.
Avatar f tn Problem is I think if you can't take one statin you may not be able to take any. But there are other drugs you can try like Niaspan (slow release niacin) and vitorin and so forth. I don't know if you are into changing your diet but if you get a chance watch the video Forks over Knives. It is how a plant based diet can reverse althroschlerosis. My husband's cholesterol was 260, blood pressure was 140/90 and weight 260. He is 6' 2" though.
Avatar f tn My doctor had already given me muscle relaxers and information pills, those help with the pain but it does not get rid of the problem. My physical Therapy have given me some exercise to do, that doesn't help at all. Just to give you a little bids of my heath history. I had angioplasty procedure done in 2005, I had two stents in my arteries.
Avatar n tn I'm on Simvastatin (40mg) which have some nasty side effects, like cramps and muscle spasms. Can you reommend an alternative?
Avatar n tn I started having severe cheek, gum, and teeth pain. No medicine over the counter or prescribed pain meds have worked. Thankfully my doc thought it might be Trigeminal neuralgia..I started an anti seizure med which makes me really sleepy, but the pain stopped.
Avatar n tn Nov 6,2008, I had ruptured achilles tendon & surgery, but while recovering, the inflamed joints in my hands and wrists were much more painful than the surgery. I am certain I had toxicity to the drug simvastatin. Just days after quitting it my hands were just sore, not inflamed, much better. The best thing to relieve the symptoms has been Nonni. It helps me sleep at night and soothes my joint pain.