Simvastatin and kidney function
Common Questions and Answers about Simvastatin and kidney function
vytorin
As you know, I was on Vytorin for years and went back to Simvastatin about a year ago. I have tested twice since on Simvatstain alone and my numbers have actually dropped a little than during my Vytorin days.
I'm only going by the Enhance trial that concudes;
"The ENHANCE study enrolled 720 patients who were randomized to receive either Vytorin, or Zocor alone. As an endpoint, investigators looked at the growth of plaques on arterial walls using non-invasive ultrasound imaging.
All of my cholesterol-related numbers are in a healthy range, and I have never experienced any serious side effects (e.g., muscle weakness, kidney and liver impairment, etc.). I have, however, had trouble sleeping for the past several years (perhaps caused by simvastatin, perhaps not). More importantly, I have been experiencing back pain for the past few months and would like to try CBD. I am down to sleep a few hours a night.
my husband has taken rimopril and simvastatin for over ten years, i met and marryed him 3 years ago our sex life was like everyone was well above average but a year later or less it dropped to maybe once week or once fortnight and as time has gone on its now worse all the time he blames the drugs he is on or iv had a heart attack is he correct !!!!!!
Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
It is recommended that liver function tests be performed before the initiation of treatment with Vytorin, and thereafter when clinically indicated. There have been rare postmarketing reports of fatal and non-fatal hepatic failure in patients taking statins, including simvastatin. If serious liver injury with clinical symptoms and/or hyperbilirubinemia or jaundice occurs during treatment with Vytorin, promptly interrupt therapy. If an alternate etiology is not found do not restart Vytorin.
my bun is 63 and my creatine is 8.02 and im 60 yrs. old.
Warnings and Precautions
Because simvastatin can affect the liver, it is used with caution in people who drink more than a moderate amount of alcohol or have a history of liver disease.
Simvastatin is not recommended for people with liver disease or high liver enzymes before treatment begins.
Possible Symptoms of Liver Problems
Several symptoms can occur in someone who develops liver problems while taking simvastatin.
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[0027] These cases involve the administration of simvastatin to patients with known Hepatitis B and C, and other causes of liver cirrhosis, mainly alcoholic. All of these patients had normal alphafetoprotein levels and were given simvastatin on a daily basis since their first diagnosis of their liver disease. None of these patients showed an elevation of alphafetoprotein during an observation period.
“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen.
http://www.idse.net//ViewArticle.aspx?
check for liver researchers and statins, the studies were from 2009 conferences and bader is the one studying sim for hbv and hcv.it is know sim has also an effect on immune system and is used on hcv with interferon and vitamin d to increase svr
the drugs not used yet are antidiabetes but researchers in florence, close to my hospital, said that they are very useful for HCC prevention or cure.
When Dad is in heart failure he needs additional dosages of diaretics. Too much diaretic can effect kidney function and too little will effect heart function. We did see a kidney specialist concerning this, and the primary care physician is in communication with him.
Dad also has vascular dementia. I know how hard dealing with memory loss can be for both patient and family. I will keep you all in my prayers.
and creatinine is very poor test for kidneys function, for example body builders can have high creatinine but everything is fine...it is too dependent on muscles and many with kidneys damage never get it abnormal
much better all the other tests
by the way hbv damages kidneys too, it can infect kidneys but not replicate there.
I have had back pain around kidney area for a few months and went to docs. She examined me and said my right kidney was inflammed. I was starting to get some pain right side under ribcage too. Mild dull ache type pain. Also still around side and back. Went back 2 weeks later and she examined again and said kidney had gone down but could still feel it. Sent me for an Ultrasound scan. I went on Wednesday this week.Thursday the surgery called me to make appointmen for a blood test (LFT).
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