Simvastatin and bleeding

Common Questions and Answers about Simvastatin and bleeding

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I am 53 and on Simvastatin 20mg nightly, plus two 81mg aspirin, one in the AM and one in the PM. I am experiencing rectal bleeding sporatically; sometimes enough to be alarmed and other times just toiletpaper streaking. I have no pain or discomfort. I have noticed that my bum feels a bit swollen during these episodes. Over the last two days in addition to the bleeding, I have no energy? Any ideas?
Hi, Simvastatin is generally well-tolerated and side effects are rare. Minor side effects include constipation, diarrhea, fatigue, gas, heartburn, and headache. Major side effects include abdominal pain or cramps, blurred vision, dizziness, easy bruising or bleeding, itching, muscle pain or cramps, rash, and yellowing of the skin or eyes. ref:http://www.medicinenet.com/simvastatin/article.htm This could be an allergic reaction to the drug. It will stop if the drug is withdrawn.
The recommended treatment for DES implants is dual therapy of aspirin and plavix up to a year. Combining plavix and aspirin increases the risk of bleeding vs. aspirin alone in patients treated for more than a brief period of time. That is the regimen followed for my DES implant. f you are in this category a prior MI and unstable angina:" In the CAPRIE trial, clopidogrel (plavix) was equivalent to aspirin for patients with a recent (but not acute) MI.
What started me down this "slippery slope" was an episode of Afib. It was after this that I was put on the simvastatin and metoprolol. I also take aspirin ( full dose ) and flecainide for the afib. Both the metoprolol and flecainide are taken at a low dose. My readings before I started the simvastatin, were ( 140 total ) HDL 33 LDL 79 and Triglycerides 139 . What has changed is that my HDL has gone down to 24 from 33 LDL has gone down to 65.
Fish oil like Lovaza is out because that acts as a mild blood thinner. I am prone to serious nose bleeding because of Efient and aspirin.
I had a heart attack in 2006, and my ulcer was bleeding at the time. I was on Nexium, and had just been switched to Prilosec. When I had the heart attack I had a 100o/o blockage and a 98% blockage and had 2 stents. I still have 6 small blockages so I cannot go off Plavix. My dr. took me off prilosec and put me on Protonix until my ulcer healed, then I took Pepcid AC 20 mg. He has recently had to put me back on Nexium for severe acid reflux, but told me to take Plavix in the morn.
And can't get it down with natural supplements or with diet and exercise?? I tried that for one year. My cholesterol was still TC 306 and my LDL was 231. What are people like me suppose to do?? Play russian roulette, and gamble with our high cholesterol because some people have serious side effects from the statins?? If a person has a side effect and has to quit that is one thing, but I don't think we should scare people who have not even tried the statins.
I had drug-eluting stents put in and I have been on 75MG Plavix, 50MG Toprol XL, 81mg aspirin, and 80mg simvastatin ever since. I never had any symptoms and I still have none. Just wondering about a professional opinion about being on these medications for life as well as the efficacy of generic drugs. I obviously am also concerned about possible restenosis in the stents.
I also take flecainide and metoprolol and simvastatin 20mg. I have started to get concerned about the aspirin dosage, after reading many articles about the dangers of taking aspirin on a regular basis, since I have had bleeding problems in the past. My cardiologist claims that my past history has not relevance to what is happening now. When I questioned my cardiologist about this he simply said " would you rather be taking coumadin? " and dismissed my concerns.
Hi, Both simvastatin and trandolapril can cause hematuria. You will need to discuss the finding of persistent microscopic hemturia and evaluate whether you need to switch to other drugs which may not impair renal function. Though indapamide has not been reported to cause hematuria, it has been known to compromise renal function. Another factor that can induce hematuria is nonoptimal control of blood pressure.
Potential side effects include bleeding, hair loss, nausea, vomiting, stomach cramps, diarrhea and leukopenia (low blood cell count). The half life (amount of time for half the drug to be cleared from the body is 42 hours but varies widely depending on the individual).
it suggests nothing they are just guesses by vitro/animal, you need thousands and thousands of patients followed for a decade at least for hcc to prove that thought exactly like they did for simvastatin, vit k2 and fish oil noting that hcc prevention is so high by nucs, simvastatin, vit k2 and fish oil that there is no need to add toxic drugs, aspirin even if low dose is too toxic for liver and gut, plus we dont know the benefit long term of making platlets low so in the end this needs full pr
I saw an EENT and he sees nothing wrong with my ears. I also stop taking all my vitamins and simvastatin just to see if that will help. Have you heard of this before. My dose was a childs dose (.5 mg).
Here's some news from the front lines (the bleeding edge of research, so to speak) on diabetic peripheral neuropathy. This may be relevant to a few of our community members so I thought it would be appropriate to share: http://www.physorg.com/news203337267.html I do not know if there might be any implications from this research on other forms of peripheral neuropathy.
i also forgot to menthion simvastatin it has activity on all hbv mutants, boost antiviral response and prevents liver cancer and decompensation improving portal hypertension a good doctor is needed to monitor improvment and if sim can have toxicity, doses used are 20mg or 40mg, link to the study here http://www.ncbi.nlm.nih.
If a bowel obstruction is due to blockage in one segment of the bowel and the remainder of the bowel looks good, surgery is appropriate radiation is a reasonable option to treat a particular area of the body when the cancer is causing significant pain or bleeding. for instance, if there is cancer in the vagina and it is bleeding, radiation can alleviate the bleeding. If there is cancer in a bone or in a lymph node that is pressing on a nerve and causing pain, radiation can reduce the pain.
All I can tell you is find another cardiologist. I am on plavix, Metoprolol,Simvastatin , and asprin and when I went in for my 6 month check up he ran a full set of blood works on me. I have a stint and he wanted to make sure I was where he thought I should be.
lovastatin, simvastatin, pravastatin, fluvastatin, and atorvastatin (cerivastatin was withdrawn from the market by the manufacturer in August 2001). The major effect of the statins is to lower LDL-cholesterol levels, and they lower LDL-cholesterol more than other types of drugs. Statins inhibit an enzyme, HMG- CoA reductase, that controls the rate of cholesterol production in the body.
DAY 1 -- blood on stool [bright red in large areas] DAY 2 -- constipated, blood on stool. DAY 3 -- constipated blood on stool. DAY 4 -- not really constipated... blood and maybe mucous or pus on stool. DAY 5 -- diarrhea, unknown if blood on stool, but did show undigested foods.. DAY 6 -- no movements, though often I feel like I need to pass a stool, but I don't. DAY 7 -- I had some right hip pain that spread to my back and front when I coughed.
I did not have a headache. I went in for an eye exam and everything looked good. I then went to my Internist and she had me go in for a Carotid Ultrasound. That also came back normal. The doctor labeled it Amaurosis fugax and told me to stay on a daily baby aspirin. I am a 56 year old female and I have a history of Bicuspid Aortic Valve and Enlarged Aorta.
After 2 ½ years of problems ( mainly shortness of breath on exertion) and after many interventions and tests which were all negative, including two left and right cardiac caths, I was referred to Emory University Hospital interventional cardiology. I underwent another cath as a way of a diagnosis by exclusion. They were pretty confident of the diagnosis they were to confirm.
I'm currently on low dose aspirin and Dipyridamole and simvastatin (even though my cholestestrol is 5.9?. The surgeon involved although very attentive and concerned about my health made me concerned as he was unsure what neurosciences dept. I have a job which is field based and I have to drive alot. However i'm not sure how calculated my risks are.
But little by little I felt worse and worse. In Sep I scratched a vessel in my nose and it would not stop bleeding, went to ER and they gave inserted a balloon to heal it, Hurt really bad, when they removed it, I fainted, my heart rate was 32. They kept me overnight for observation, my gp wanted me to follow up with my cardio doc. My gp thought I was having anxiety attacks and even got a rx for that but never took it.
You're in the right place if you want off the Tramadol! You can do it! I believe in you!
I revisited the issue a few weeks ago because a doctor a year ago put me on Simvastatin and a new doctor wanted to raise the dosage from 10 mg to 20 mg and I suddenly decided to look up medical research. Surprise: the Pharmacovigilance Working Group of the European Medicines Agency put out a warning in Nov of 2009 telling doctors that if a patient develops interstitial lung disease (which Pulmonary Fibrosis is) he should be taken off statins immediately! I took myself off immediately!
Platelet aggregation is probably a good thing if you're bleeding out because then you clot and the bleeding stops. If cardiac health is the issue you probably don't want increased platelet aggregation because you don't want your blood to clot. A blood clot in a vessel that provides blood to the heart can result in a coronary thrombosis or myocardial infarction. A clot in a vessel that supplies blood to the brain can result in a stroke.
i d definitely go in to etv+pegintf+simvastatin your levels of hbsag are the same as otan and she/he cleared by 16weeks on pegintf+sim so you are in such a favourable status that hbsag may even be cleared before the first round of tests which is ususally at 12-24 weeks
by the way forgot the news on cofee or even better green coffe extract and simvastatin the action of simvastatin on cancer prevention is activation of apoptosis of cancer cells (the cancer cells suicide themselves)
Metoprolol, Lisinopril, Plavix, Asprin, and Simvastatin. At night, if I'm feeling extra anxiety I take Lorazepam and I'm a lousy sleeper so I take 1/2 an Ambien. Talk about drug city, I'm on ten different meds! When I was experiencing my heart attack I thought, if I get through this, I'm going to count each new day as a blessing. I didn't anticipate that each day would be painful.
At present time I am on Coreg CR, sivastatin, 81 mg. aspirin and 3000 mg of fish oil. I was following a low-salt diet at the advice of my doctors but have since been instructed to increase my daily salt intake. I have had a echocardiogram w/bubble test, stress test, several ultrasounds with results indicating that a heart cath is not necessary at this time. My questions are 1. Has anyone experienced skin sensitivity around the heart area? 2. Muscle and joint discomfort? 3.
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