Acetaminophen, aka Tylenol, works in the brain and central nervous system to deaden pain, although researchers do not fully grasp how it works .
For more severe short
pain, as after an operation, or long-term pain, many doctors turn to opioids. Opioid drugs plug into an existing network of receptors located in your brain, spinal cord and body. Under normal conditions, this system works with your body's naturally produced opioids to control all kinds of processes, including pain.