Yes I gained a fair amount of weight on Depakoate (another brand name for Epilim) and
Seroquel. I do know I had less of a problem with weight gain with Lamictal and that among the current generation of antipsychotics, Abilify, Fanapt and Saphris are the least likely to cause weight gain but each person responds differently to each medication. Ask your psychiatrist about available options.