role of estrogen in osteoporosis

From a tiny, underfunded clinic in Glasgow, Scotland, he set up one of the first clinical trials of estrogen replacement therapy for bone loss in postmenopausal women. Lindsay's star was rising. His next project had big commercial implications and got the attention of the drug industry.

Menostar is an ultra, ultra low-dose estrogen patch (0.014 mg/day) that has recently been approved for unopposed estrogen use in postmenopausal women. It is indicated for bone protection only and does not offer any vasomotor symptom relief. You can get these patches prescribed. It is very difficult to precisely confirm a diagnosis without examination and investigations and the answer is based on the medical information provided. For exact diagnosis, you are requested to consult your doctor.

After menopause, women lose calcium from their bones at a much faster rate than men due to the lowered levels of estrogen. By the age of 65, women have 3-5 times the risk of fractures than men." So this points to estrogen. Also, I found this site to be interesting. http://www.wrongdiagnosis.com/o/osteoporosis/causes.htm This site lists 200 causes for osteo plus it has a link to what they called their "full list of causes for osteoporosis".

There is lots of osteoporosis in my family, both Dad's and Mom's sides. So I take calcium and D, and I am also on a low dose of estrogen with protesterone 12 days a month. Not great, since research suggests issues with the heart or breast cancer from hormones. But since I know I'll get the bent back otherwise and don't know that I'll get problems from the HRT, I'm OK with it right now. Maybe later I'll talk to the doc and see what else can be done.

t heard of a diet to help this but I do know that estrogen dominance can have a role in it. Google estrogen dominance and you will see some things you can do to help reduce that and some may be food related. Good luck with your recovery.

I'm a 59 y/o postmenopausal female that was recently diagnosed with osteoporosis with a T score of -3.2. Was sent to an endocrine doc and did several blood tests as well. The doc wanted to start me on hormone therapy and injections based on my bone density test. I was prescribed the estrogen Duavee 20 mg daily and Prolia 60 mg shots every 6 months. Has anyone had experience with Duavee or Prolia?

Thank you for your response. Your take on the osteoporosis was very helpful. I also was on Fosimax for bone loss. It did not make a difference. So now I am off it. But I resent the whole ordeal. I had to take increased amounts of calcium. I did not realize the decrease in estrogen of menopause made me constipated and the added calcium made it even worse. Half the time I was using laxatives and I feel negating the effects of the fosimax and calcium. I was such a mess in a bad cycle.

Just like women lose estrogen with age, men lose testosterone which leads to osteoporosis in both sexes. Take care!

, are a diverse group of naturally occurring non steroidal plant compounds that, because of their structural similarity with estradiol, have the ability to cause estrogenic or/and antiestrogenic effects. Researchers are exploring the nutritional role of these substances in the regulation of cholesterol, and the maintenance of proper bone density post-menopause.

I have no family history of osteoporosis. I completed 24 weeks of tx in December 2011. In January 2012 I had a bone density test because my GP said I should have one since I am post menopause. My results were excellent and I do not even need to take calcium. BTW I never had a bone density test before. I hope you all that are seeing this result can get treated and reverse your bone loss. I am posting so you all know that not everyone will have this issue. Just get checked and don't worry.

Two weeks ago I had a medical test,(stereotactic biopsy), where I had to lay on my abd/side for over an hour. In the middle of the test I had intense pain in my lateral rib are where I was laying. I could barely breathe & the pain was intensified with inspiration. The radiologist said that was a first for him doing that procedure, he had never had that happen before. My ribs are slowly improving over time but I'm wondering if I have a stress fracture.

I'm recently in recovery from 11yrs of anorexia. I have severe osteoporosis as a result. I am 22 years old. I was put on birth control for the estrogen to help replenish my bones, and return my period. (I do not menstruate without the pill) I have doubts of my being able to actually carry a child in the future, but was considering a surrogate mother. Is there anyway to tell if I'm even producing eggs anymore? Is a surrogate, with my egg and husband's sperm possible?

It sounds to me like your doctor is more concerned about your estrogen levels in relation to the cancer rather than the size of the fibroid. So, from that standpoint, it seems like a good choice. For peace of mind, you may consider getting a second opinion. Good luck on making your decision!

Osteoporosis will come and calcium, magnesium, vitamin D, vitamin K, and boron are not enough. I had osteopenia in 2009 and -3.7 osteoporosis in 2014. I took vitamins all my life and started Damiana, Kava Kava, etc. when menopause started in 2002. If I could do it over, I would take the HRT. BUT...now they are realizing that you can be on an ultra low dose estrogen and it works great on the bones AND menopause symptoms. The ultra low dose is 0.014 mg (14 mcg.).

How are you? Until menopause, the ovaries make most of your body's estrogen. When the ovaries are removed, estrogen levels suddenly drop. This change causes early menopause and increased osteoporosis risk When taking hormone therapy after an oophorectomy it is important to take estrogen plus progestin (hormone replacement therapy). The progestin protects the uterus from the increased risk of estrogen-related endometrial cancer. You can read more about this through this link: http://www.

ve never come across any data showing a relationship between osteoporosis and MS. However, sufferers from both are overwhelmingly female. In general, MS begins to develop at a younger age and osteoporis occurs post-menopausily. One thing you need to keep in mind, now that you have both, is that steroids used to treat severe exacerbations are very hard on bone density. If you need steroid treatments, try to space them widely apart, and make them a last rather than first resort.

s not enough strontium in our food to have a significant effect if you have osteoporosis already, so if you’re suffering from this condition, you should take strontium in supplement form. But if you don’t have osteoporosis, it’s a good idea to eat foods that contain more strontium to prevent it from occurring. The largest amounts of strontium are found in spices, seafood, whole grains, root and leafy vegetables, and legumes.

Several of my friends after menopause said that taking estrogen replacement helped or completely stopped their headaches. But I've heard it can go either way. I never got any estrogen in my system from the estradiol gel. You should instead wear an estrogen patch. And your depression is very likely from the lack of estrogen. Don't mess around with depression. It is tied to a number of physical diseases, such as osteoporosis.

Does this surgery cause menopause for her and cause osteoporosis, hot flashes ,does she need hormone therapy or because of having one ovary no need ,I really appreciate to help me since I am to worry .

I take the K2 and eat boron-rich foods in order to improve absorption. I had read, though, that lactoferrin, in addition to its role in immune function, plays a role in bone growth (e.g., http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1183439/), so thought that it might be a good option, if safe.

Premerin contains only estrogen and is used primarily in the prevention and management of osteoporosis, vasomotor symptoms and vaginal dryness associated with menopause. Although the relationship between estrogen and autoimmune disorders is not clear, such hormones can stimulate some chronic infections. This may be why it can be associated with DILE (Drug Induced Lupus). The majority of Lupus patients have chronic infections.

Femara is used in estrogen receptor positive breast cancers to prevent cancer recurrence. It decreases the amount of estrogen in the body. Estrogen protects bone strength and if estrogen levels fall then there are increased chances of osteoporosis which can result in fractures. So calcium supplements are prescribed along with femara.There are few studies that do suggest that calcium supplements increase the risk of heart attacks. Discuss it with your doctor.

Mayfly, It is so hard to say if the patch of Vivelle caused the weight gain. This is such a complicated subject. I am wondering if your body was making Estrogen in the form of Estrone (which is the 'menopause' estrogen that is made as a by-product from the fat in our system... and this fat is what causes the fat around our middle section so that it is readily available for use by the body since women's bodies crave estrogen)...

Some professionals think that it is a precursor to the development of osteoporosis, a type of bone disease. Despite this, not all cases of osteopenia lead to that condition. Causes Various factors can be behind the development of osteopenia. As mentioned, people with hypothyroidism may have this issue show up. Due to the loss of estrogen, it is relatively common in post-menopausal females. Certain lifestyle factors can also worsen the condition.

Role of estrogen in osteoporosis

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