Ribavirin solubility

Common Questions and Answers about Ribavirin solubility

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Avatar m tn Methadone has a slow metabolism and very high fat solubility, making it longer lasting than morphine-based drugs. Methadone has a typical elimination half-life of 15 to 60 hours with an average of i would say about 22. However, metabolism rates vary greatly between individuals, up to a factor of 100 ranging from as few as 4 hours to as many as 130 hours, or even 190 hours. So it's hard to say.
Avatar m tn The water solubility of bilirubin allows the bilirubin to be excreted into bile. (Bile then is used to digest fats.) Total bilirubin, if I remember correctly, is the conjugated hemoglobin, since there is also another portion that is not conjugated. What the elevated total bilirubin means at this point is 'something' is going on, but you may need more information before your doc can determine the cause.
4670047 tn?1375730401 I was just wondering how long some of you took the ribavirin after your last shot. I'm going to call the Dr. On Monday and ask. But I'm just a little anxious, my last shot is Mon. night. Thank you!
Avatar n tn How long that ribavirin stay's in my system after doctor tells me my bloodwork came out good and i can get of that medizin.
Avatar n tn I am running short on my Ribavirin. Does anyone know of any resources? What would be the least expensive way, assuming that my doc won't give my Rx.
Avatar m tn The main requirements for them are (1) high IFN-inducing activity, (2) absence of side effects, (3) wide spectrum of antimicrobial activity, (4) broad therapeutic security and, (5) good solubility in water and biologic liquids. IFN inducers stimulate IFN production in different cells and organs, and that determines the strategy for their application. Amixin (OOO "Lancepharm," Moscow, Russia) induces IFN-?/? production mostly in T cells. Cycloferon (NTFF "Polysan," St.
Avatar n tn However, factors that can affect absorption include oral pH, salivary enzymes, lipid solubility, and molecular weight (molecules may be too large to pass through the mucous membranes). A sublingual product, specifically created to ensure effective absorption, is recommended.
1331115 tn?1536362140 INCIVEKĀ® (telaprevir) is a prescription medicine used with the medicines peginterferon alfa and ribavirin to treat chronic (lasting a long time) hepatitis C genotype 1 infection in adults with stable liver problems, who have not been treated before or who have failed previous treatment. http://www.incivek.
10318302 tn?1409256668 Ribavirin is definitely not a walk in the park but the combo of the two (Riba & Interferon) is definitely much worse. My husband tried triple treatment with Incivik and lasted only 5 weeks on it. It almost killed him. He just completed the Sovaldi & Ribavirin treatment for 24 weeks. (He's gt 1a). He definitely had a rough time because he has hepatic encephalopathy and it was worsened with treatment BUT the important thing is he made it through treatment.
Avatar f tn s assistant called yesterday and said I am anemic and to take a shot of procrit. Also to reduce to 400mg/day ribavirin instead of my 800mg. I am in week 15 and have been UND at week three on triple therapy with incivek. Genotype 1a. Weigh 140 lbs. I was on 1000mg for 6 weeks and for the remainder of the time have been on 800mg. Yesterday I started on 400 mg and am worried about relapse. What is the role of ribavirin and just how important is it to SVR? I am on course for 24 wk.
Avatar f tn I'm in the Telaprevir trial in week 13, so I finished the Telaprevir (or placebo) this past Wednesday. A day or two before that my scalp started itching. Yesterday it spread to the point that I had the itchies on almost half my body. Then I noticed tiny bumps where it itched worst. I took Benadryl, which didn't make it totally go away but brought it under control. It's better today but not gone. Just took another Benadryl.
Avatar f tn This was shown in a retrospective analysis of a large, randomized, placebo-controlled trial in which patients who achieved RVR had an SVR rate of approximately 90% regardless of whether they received peginterferon alfa and ribavirin, standard interferon and ribavirin, or peginterferon alfa monotherapy. In addition, the likelihood of SVR patients with genotype 1 infection who achieve an RVR does not appear to be affected by shortening the duration or reducing the dose of ribavirin.
Avatar m tn High Ribavirin? I am thinking about trying tx in a clinical trial with high riba. (about two times normal). It seems like a lot of people here who did clear with SOC had more side effects than those who did not clear. I had few side effects but also did not clear. Maybe its the riba I thought jmjm530 cleared using lots of Riba? Anyone else do this or have thoughts?
1148619 tn?1332010984 Studies with Victrelis showed the patient was given weight-based ribavirin (600-1400 mg/day orally divided twice daily. At 114 lbs 800 mg of ribavirin would be in range but if you tolerate 1000 mg that it all the better and at this point I don't think you're being over prescribed. It's important to get that viral load down during the first 4 weeks and ribavirin stops the virus from replicating.