ribavirin route

I think that if you make it all the way through with Telaprevir/ribavirin/interferon for either 8 or 12 weeks and then ribavirin/interferon for the rest, up to the total of 24 weeks, odds of cure are probably more like 85% to 90%. BUT, if you don't tolerate the treatment well, you'll need to have a plan B. Your plan B will depend on what aspect of treatment turns out to be the problem.

For the management of anemia, ribavirin dose reductions should be used (refer to the prescribing information for ribavirin for its dose reduction guidelines). If ribavirin dose reductions are inadequate, discontinuation of INCIVEK should be considered. If ribavirin is permanently discontinued for the management of anemia, INCIVEK must also be permanently discontinued. Ribavirin may be restarted per the dosing modification guidelines for ribavirin.

You started two days before your shot? I'm not sure how many people on here have just taken those two drugs who might be able to share. It actually takes a while to find the side effects of oral Ribavarin that's not the inhalation route or listings that are not lumped together with peginterferon or interferon: http://www.webmd.com/drugs/mono-2279-RIBAVIRIN+CAPSULE+-+ORAL.aspx?

6 Clinical studies have shown that when subjects with HCV genotype 1a have this polymorphism at baseline, the efficacy of simeprevir in combination with PEG and ribavirin is substantially reduced.6 Consequently, alternative therapy should be considered for such patients.6 http://education.questdiagnostics.

) a) I doubt if it matters much if you’re off a few hours with your ribavirin dosing. I imagine the original trials were conducted 12/12 hours, but ribavirin has an extremely long serum half-life; once serum concentration is established (CMAX) it “sticks to your ribs” :o); a few hours either way shouldn’t make too much difference. More important, perhaps, to take it when you won’t forget a dose; and take with food if possible.

First time was monotherapy with 3 shots of intervon a week as that was all there was I think about 1995 the first time I treated. Later it was interferon and ribavirin and then one more with interferon ribavirin and a trial drug all with no success. I was a total non responder my viral load never decreased at all. I was diagnosed with cirrhosis Jan 2008.

Genotype 1 is the most common in the US. The standard course of therapy for genotype 2 or 3 is pegylated interferon plus ribavirin for 24 weeks, increasing to 48 weeks for hard-to-treat genotype 1. Genotypes 2 and 3 also have a response rate of 70%-80% in most studies, If you don't have advanced liver disease (you will need a biopsy to know) there should be treatment within the next year, for people that haven't treated before, the cure rate is 90% or better.

We have tried the drug companys medicare and free clinics. No help from any. If anyone knows any oter route we could attempt please let me know.

I was just wondering how long some of you took the ribavirin after your last shot. I'm going to call the Dr. On Monday and ask. But I'm just a little anxious, my last shot is Mon. night. Thank you!

How long that ribavirin stay's in my system after doctor tells me my bloodwork came out good and i can get of that medizin.

I am running short on my Ribavirin. Does anyone know of any resources? What would be the least expensive way, assuming that my doc won't give my Rx.

I'm in a 7977 study for genotype 2 and 3, on the SOC arm. If I hadn't gone und by wk 12 they would have rolled me over to 7977....I think my tx nurses were almost hoping I'd go that route; that 7977 has been incredibly successful! I would not have been concerned at all. What are the circumstances, did you not go und or are your platelets too low? Or?

Have any of you seen the new study out of Johns Hopkins regarding comparing the two Pegs? Apparently they also looked at lowering the dose of ribavirin (and interferon) when anemia occurs and found that actually improved the success rate of SVR when compared to people who toughed it out and stayed with the same dose. I was floored when I read this and wish I knew enough to know just how good this study really is. I have a lot of respect for Dr. Sulkowski.

Yea, I got approved for Vosevi. After going through resistance testing, seeing Hepatologist an hour and a half away.., I have been approved for new drug by Gilead (came out after Harvoni). My doctor didn't want me to go the Harvoni route. I did ask about it. Since i am non-cirrhotic and have resistance issues, and I am a treatment failure patient.., all these things made me be a good candidate for Vosevi. NO RIBAVIRIN. and NO INTERFERON. Very glad about that.

Newer treatments that look to be here around the first of the year for type one is a lot shorter but still have Interferon and Ribavirin in the mix. Someone that is type 2 should jump at the newer treatments as there is no interferon, as for type 3 while the treatment is the same as type 2 the success rates were not as great. Time is on your side, just keep in mind Hep C can cause other problems besides the liver.

gov/pubmed/1695539?dopt=Abstract), (and assuming a drop in VL no doubt) Finally ribavirin metabolism involves several cytochromes. but primarily 2D6 and 3a. Here I would focus on the cyp 3a, because the telaprevir or boceprevir are also reliant on this cytochrome. Meaning this cytochrome will have plenty to do while you are treating. My SUGGESTIONS to the patients, and the high risk or late stage patients especially would be 1.

You can take supplements in the B family, but during treatment I think you should only go the natural route, or ask your Doc. Sometimes if your Hmg goes extremely low, then cam give you a blood transfusion, or a rescue drug to raise your #s. What I've noticed lately when the #s go low, they reduce your Ribavirin. Alot of people sail thru, and with a 12 week protocol it typically doesn't happen until your near the end of treating, and then they do the watch and see approach.

Ribavirin route

Common Questions and Answers about Ribavirin route

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