Ribavirin drug information
Common Questions and Answers about Ribavirin drug information
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has anyone heard of the drug, Bucephavir, my doc said I should wait for it. Hep C 1A did 48 months, cleared at 12 weeks, but it back.
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Ribavirin, used in combination with an interferon, is used for the treatment of chronic hepatitis C. Ribavirin is a Federal Drug Administration Pregnancy Category X product, indicating that its use is contraindicated in women who are pregnant. The package insert also states that ribavirin is contraindicated in men whose partners may become pregnant. The Ribavirin Pregnancy Registry operates in the United States and actively monitors pregnancy exposures to ribavirin.
I also heard it will have a possible 80% cure rate. Can you give me any information on this drug so I can pass it on and talk to my Doctor here in Atlanta about it?
They most promising drug trials do contain interferon and ribavirin right now but they also ADD a new drug to them that has had great success treating prior relapsers - some of them many more times than two attempts. The drugs will hopefully be available in the next year so even if you cannot get in to a trial there is still hope.
I am surprised that your doctor does not have this information yet. It is very common information and you can google up telapravir and bocepravir to start.......
With regards to ribavrin and sperm, in some respects, the jury is still out. Ribavirin can cause changes in the actual structure of the sperm. The drug is also found in semen. It is unsure whether or not the drug is present within the sperm cell or not. There is a registry of paternal ribavirin pregnancies carried to term and there have been results of successful presnancies.
Any thing i can find out before hand is helpful God bless you all. Thanks so much for all the value information I have found here. Dont really know how to read lot of it dont understand the short cuts and abbreviations .
t have a link to give you right now), the side effects associated with Telaprevir are GI symptoms, anemia, and rash. Since Ribavirin also causes anemia, there is a synergistic effect when Tpr and Ribavirin are taken together. Ribavirin causes rash, too, but sometimes the Tpr rash is severe enough that subjects have had to stop tx. So yes, the symptoms are similar to SOC tx, but they may be magnified when the third drug is added.
Congratulations on starting tx, glad you're doing well.
Hey everyone...Incharge08 (I'm brain fogging bad today, can't remember her name), has had her insurance terminated and is 3 months into treatment...she is a 1a with a 1/1 bx, so she has a really good chance of SVRing if she can keep going...her meds run out next Friday...I'm checking around to see if there's anyone out there who has leftover Peg or Ribavirin and would be willing to send it to her if she decides to keep txing...
t know where that doctor is getting his information from. The drug company will tell you the same thing if you contact them. That doctor is being seriously irresponsible in making that recommendation and I don't have any problem at all in saying you should ignore his recommendation and wait six months. Ribavirin is considered very teratogenic.
te·rat·o·gen
[tuh-rat-uh-juhn, -jen, ter-uh-tuh-] Show IPA
–noun Biology .
Gilead Sciences Inc. discontinued dosing of a four-drug HCV regimen consisting of tegobuvir (GS 9190), ribavirin, pegylated interferon and either GS 9451 or GS 9256. Gilead said the regimen led to two serious adverse events in two separate studies. The company did not say how many trials would be affected but added that the timelines of the studies will remain unchanged. Dosing regimens that include GS 9190 but not interferon will continue as planned."
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Refer to the prescribing information of peginterferon alfa and ribavirin for a description of adverse reactions associated with their use.
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
The lack of anticipated drug-drug interactions between daclatasvir and the calcineurin inhibitors coupled with its potent antiviral efficacy make this agent in combination with peginterferon and ribavirin an attractive antiviral regimen worthy of further study in liver transplant recipients with recurrent HCV. © 2012 American Association for the Study of Liver Diseases
Best to you...
Does anyone know which drug in trials was stopped this week? I'm wondering if it's the polymerase inhibitor.
I am on the last 30 days of treatment with Harvoni combined with ribavirin. Although I have experienced many side effects over the course of treatment they were not dibilitating and did not last more than a few hours before resolving. The main side effect is fatigue that worsens as your day progresses. I have been tuckered out by 6 pm most days and in bed before 8 pm. I am thinking that is due to the Ribavirin. Now that I am in the last month of treatment, the fatigue is not as pronounced.
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