Ribavirin and interferon

Common Questions and Answers about Ribavirin and interferon

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Avatar m tn Use at least 2 effective forms of birth control while either sexual partner is using interferon alfa and ribavirin, and for at least 6 months after treatment ends. •Use at least 2 non-hormonal forms of birth control while either sexual partner is using Incivek with interferon alfa and ribavirin. Keep using 2 forms of birth control for at least 6 months after treatment ends. •If you are a woman, do not use Incivek with interferon alfa and ribavirin if you are pregnant.
Avatar n tn Dose of ribavirin is weight-based (<75 kg = 1000 mg and ≥75 kg = 1200 mg). The daily dose of ribavirin is administered orally in two divided doses with food. Patients with renal impairment (CrCl ≤ 50 mL/min) require ribavirin dose reduction; refer to ribavirin prescribing information. SOVALDI in combination with ribavirin for 24 weeks can be considered as a therapeutic option for CHC patients with genotype 1 infection who are ineligible to receive an interferon-based regimen.
Avatar n tn Ribavirin has a longer half life than interferon. The levels for both gradually come down to zero over time. It is a few weeks with interferon and a few months with ribavirin.
Avatar m tn Many clinical trials have shown that high exposure to ribavirin and maintenance of ribavirin dosing during interferon-α treatment courses is strongly associated with SVR rates, demonstrating that ribavirin is a key player of treatment success in chronic hepatitis C. Accumulating data are available today that aim to explain the distinct molecular mechanisms of the ribavirin mode of action. Generally, none of the proposed mechanism seems to account solely for the clinical benefit of ribavirin.
Avatar n tn However as a genotype 3 you are eligible for the Sovaldi/Ribavirin treatment for 24 weeks with no interferon. I am a genotype 2 and am 5 weeks into 12 weeks of Sovaldi/Ribavirin treatment and have had NO side effects at all, zip! I can't be sure how the next 7 weeks will be but I'm feeling good about it. Side effects vary person by person and I can't promise you would have no side effects but all in all most people are tolerating this treatment very well.
Avatar m tn I thought ribavirin had the main impact on neutrophils and interferon had a secondary effect. The Soza paper and many others I came across indicate that interferon has the pirmary effect on neutrophil count reduction with only a small if any effect by ribavirin. Patient neutrophil counts as a function of time into treatment also support this. If ribavirin was the primary cause then it would take 4 or more weeks before neutrophil counts were impacted.
Avatar f tn He was recently feeling tired and decided it was time to get checked again, and lo and behold the dragon is back in full swing. The interferon almost killed him before and the dr. said he is not a good candidate to try again so they prescribed Sovaldi, Olysio and Ribavarin for 12 weeks. He has a wonderful dr who was able to get our insurance to approve the off label treatment.
Avatar f tn She was treated with interferon peg interferon and ribavirin for one year but the pcr was not clear and even she became more sick and her fever could not be controlled for full one year even she was hospitalised. Now she is on sofosbuvir and ribavirin again and after one month hcv qualitative pcr is undetected.
Avatar m tn My husband was treated with interferon and ribavirin several years ago and the side effects were horrible as you already know. Unfortunately, it was un-successful. He is now being treated with ribavirin and sovaldi. I understand this is a rather new treatment just approved by the FDA this year with minimal side effects compared to the previous treatments. It's been 2 months and all is good. Labs look good and it appears to be working.
13733970 tn?1431266965 Harvoni with or without Ribavirin? Viekira Pak with or without Ribavirin? Sovaldi with Ribavirin? Sovaldi with Olysio? Interferon and Ribavirin? They all have different side effects and depending on which treatment you are asking about most experience more side effects with certain treatments like interferon and Ribavirin and generally much less side effects with Harvoni with out Ribavirin. In fact many report little to no sides with Harvoni or occasional headaches.
315737 tn?1407298997 s the third time for me too. I did Ribavirin and Interferon 3x/week in 98 and Victrelis, Ribavirin and Interferon in 2012. I had the same results, partial response but didn't clear. I'm on Sovaldi, Ribavirin and. Interferon now. I start week 7 of 12 on Friday. Haven't found ou my 4 week VL yet, but am hoping for good news! Go get that dragon!
Avatar f tn Yes the new drugs boceprevir and telaprevir will include interferon and ribavirin as part of the treatment. If you respond quickly to treatment with these new drugs you may be able to treat for 24-28 weeks rather then the traditional 48 weeks for genotype 1 with just interferon and ribavirin. Side effects vary enormously from person to person. Some have few to none, some have many, and the bulk of us are somewhere in between.
Avatar n tn Upon analyzing over 3,000 people being treated for Hepatitis C with pegylated interferon and ribavirin, Mark Sulkowski and colleagues found this to be true even when ribavirin reduction or ESA administration was given to reduce anemia. In fact, the rates of achieving a sustained virological response were greater as the severity of the anemia increased.
Avatar f tn I think the main one that I can isolate to the Riba is the total body dryness and the itching/rash. After just a day and a half without it (and everything else) I am much less thirsty. The rash and itching still persist, though.
315737 tn?1407298997 Check with your doctor first please. I changed my dosage up a little bit and it put me in a world of hurt. Apparently, the Riba works with the Interferon and the Interferon breaks down molecularly and there is a perfect balance...if you haven't found out already. Please call your doctor first and dont try to take shortcuts on your own like I did....trust me on this one.
408795 tn?1324935675 At best, infected individuals have a 50 percent chance of triumphing over the virus by enduring standard combination therapy, a notoriously challenging treatment with pegylated interferon and ribavirin medications. Most experts believe that the success rate of these drugs would be much higher without the burden of their potentially serious side effects.
10318302 tn?1409256668 After two tries with interferon and rib and now Sol and Rib I believe you are right on with that observation. It's a very nasty nasty drug. I had to do it for 6 months. It's very doable I think for three months. At least it was for me.
179856 tn?1333547362 The study includes treatment arms that are evaluating 12-week, response-guided regimens of two- and four-drug telaprevir/VX-222 combination therapy, given twice daily, with and without Pegasys(R) (pegylated-interferon alfa-2a) and Copegus(R) (ribavirin). Trial sites for the two- and four-drug ongoing arms completed enrollment in October 2010.
476246 tn?1418870914 To assess the efficacy and safety of peginterferon alfa-2a/ribavirin in genotype 1-infected patients treated for up to 12 weeks with peginterferon alfa-2b/ribavirin but not achieving EVR (non-EVR) or non-tolerant (NT) due to depression, fatigue, flu-like symptoms, or injection-site reactions. Methods: NTs were treated for an additional 36 weeks and non-EVRs for an additional 60 weeks with peginterferon alfa-2a (180 mug/wk)/ribavirin (1000/1200 mg/d).