A positive ANA (anti nuclear antibody) can be seen with various autoimmune diseases, as well as infections, cancer, lung diseases, gastrointestinal diseases, hormonal diseases, blood diseases, skin diseases, in elderly people, or people with a family history of rheumatic disease.
The centriole/centrosome proteins are found with Raynaud's phenomenon, scleroderma, Sjögren's syndrome, limited scleroderma (CREST), and viral infection.