Have you called the ask a nurse hotline from
Rebif? Their website says they have one, and suggests you call them if you experience any reactions
or have questions. My hubby has called the Betaseron hotline, and they are great help!
Rebif website also says you can apply a warm cloth or compress after injection. And that you can apply a topical OTC like hydrocortisone cream, Aloe Vera, Oatmeal products.
Lastly I always think it's best to check with your own Dr, just to be safe.