rebif half life

i started rebif about a month and a half ago.since then depression has been rampant!!!night sweats have been rampant!!!im also on wellbutrin for depression.im told that it takes roughly three months for rebif side affects to subside>can anyone share there experience with rebif.ive been dx with relapsing ms recently,august fifth to be exact and my life is upside down!!!!!!im talking on the virge of mental breakdown.any input is welcome...

7 IU/mL (mean ± SD), with a median time of peak serum concentration (Tmax) of 16 hours. The serum elimination half-life (t1/2) was 69 ± 37 hours, and the area under the serum concentration versus time curve (AUC) from zero to 96 hours was 294 ± 81 IU h/mL.

The half-life of a drug is how long it takes for half of it to be eliminated from the bloodstream. Hope that helps.

It has a very long half life, though I can't give you specifics. The dose and how long you were on it does factor in. Your doctor should be able to help you with your questions on this.

So, in March, I took 4 weeks off of Rebif. By the middle of the 4th week, I was able to drink 2 cups of coffee a day, with Half & Half and even eat cake for my 39th wedding anniversary. (I ate cake for 4 days-no diarrhea) I restarted the Rebif, the 1st week of April, and the diarrhea returned, after the 2nd injection. I can't drink coffee, etc. My MS Lifelines nurse came out, to see if I had enough fat to use the new Rebidose injector.

He had so much more knowledge and was worth every penny. He told me that Rebif only stays in the system for half an hour but the benefits from it last a month or more. He said i dont have to wean myself off and that i can stop taking it right away. I just need to get a chicken pox vaccination in the next week as i have no immunity and it is very dangerous to catch while pregnant. After that i can start trying for a baby woohoo!

Thankfully he tolerates it well, as his Neuro said that is half the battle. Prior to the definitive MS diagnosis, for approx 3 wks while hubby was undergoing all the tests, we lived with the "99% sure he has a motor neuron disease, most likely ALS/Lou Gehrig's." So as bad as it may sound, when we went for the results appt, the nurse actually told us it was good news, it's MS. I cried and laughed at the same time thru most of that appt.

I took my first shot of Rebif today. I gave myself the shot and i thought this is great no stinging, no redness, no lump like i had with Copaxone. Then WHAM!!!! I had abdominal pain about an hour after the shot it lasted for about 6hrs The only thing i could compare it to was a 6hr nonstop labor pain. We will see what happens Monday when i take the next shot. Does anyone else get this abdominal pain on Rebif.

Hello. I have been on Rebif now for just over three years after nine and a half years taking Avonex. Have been very consistent in making sure to take my shots. Having a short term memory moment, realized the other day while taking my 2nd to last shot of my current distribution; This being true, tomorrow will be my last shot with a schedule to take the first of a new packet on Saturday, Dec 22nd. Many thanks if you can supply me with the appropriate phone number to order a next batch.

Hi, I just began my titration of Rebif, with 8.8 mcg for 2 weeks, so I moved up to 22 mcg on Friday, January 29th. So far, my side effects were flu like symptoms and increased tremors (with 8.8 mcg). Today, Saturday 30th, my side effects include flu like symptoms, extreme aches and pain throughout my body, all the way down to my bones, like I have been beaten severely with a baseball bat, but also I'm running a fever. Normal body temperature for me is 96.

I was on fire. Drenched in sweat. I have never sweat in my life like I did that night. I was on my room half asleep.with air conditioner on and my ceiling fan on high. Do you use the auto inject method?

Hello, I have to try Rebif before my insurance will consider me for an oral DMD (since I've already been on Copaxone). I don't know too much about Rebif. I do know that it's an interferon and can cause flu like symptoms and I think it's intramuscular injections. Do the injections hurt? Do you do the injections or does a nurse come out and give the injections? Are the injections in your legs? How often do you have to get the injections?

I have been on both Rebif and Copaxone. I was on Rebif for about 5 years, and I have been on Copaxone for two. I didn't have any problems with the Rebif except for the high liver functions. That is why I am on Copaxone. I think there is no difference in the injection pain. They both were very minimal. My worst pain was in my arms for some reason. The daily injections aren't bad, especially since you don't get sick.

decided to quit taking it on a monday felt fine all week untill sun when i went into serious withdrawl! so as far as half life im not sure? but you can bet i was back on it mon! so i guess it was in my system for 6 days after i stopped. p.s.

?? Does anyone know the Half life of SUBOXONE - Beprenorphine.? I HEARD it was 70 hours, but that's what I heard....unsure if that is even accurate?

whats the half life for syntriod. about how much time does it take to build up in you and also leave your system?

I'm also Secondary Progressive, but not as severe as you, I'm now a 5.5 on the scale. I was on Rebif for 15 months, sicker than a dog and so weak and in so much pain the whole time and the MRI's showed it clearly wasn't working for me. My last neuro had me stop taking it and wanted me to try Novantrone, but the I wasn't ready to do that. I've been off the Rebif for about a year and a half and have been stable and have felt so much better for the past year. I was a 7.

Hi all- I am just writing to let everyone know that I am about to start tysabri infusions in late June. My neurologist thought that based on the "large lesion load" in my t-spine that Rebif was simply not working for me. Because I am young, and he wants to "give me the best chance" for quality of life he thought tysabri is the best choice for me (despite the risky side effects).

I started on the Rebif Titration, accepting of what was now my life, and broken hearted. We are more than six-weeks into the Rebif now, and my acceptance has turned to outright frustration and depression. I have heard from friends of friends that they cured their M.S. with dietary changes and lifestyle changes. If this is possible, and how I would like to believe it is, then could I get off the Rebif boat?

I have been taking Rebif injections, since January 2010, and I have never missed a single one, until now. Up until January 1, 2012, I have received my Rebif injections, free of charge, due to the fact I had no health insurance. I became eligible for Medicare, on January 1, 2012, and so I have had to wait for MS Lifelines to decide whether I'm still eligible for their "free of charge" program.

Hi all, I have been on Rebif for about 18 months now and it makes me constantly feel like ****, sorry for the expression! What I mean is I just never feel normal. I came off it for 2 months in Jan to try for a baby, I have never felt so great, I had a relapse after 6 wks so my neuro said trying for another child was a bad idea for me and my family, so I went back on the Rebif. I was just thinking should I try another dmd to see if it makes me feel better or are they all gonna be the same?

Rebif half life

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