Raloxifene vs tamoxifen
Common Questions and Answers about Raloxifene vs tamoxifen
evista
It does act as an anti-estrogen but also acts like estrogen in that it prevents the bone loss that other drugs like Tamoxifen may cause. It actually has the same side effects as Tamoxifen but not every person will experience all of these side effects or to the same degree. I'm not sure what you mean by "it made me ill" ... you may have the same side effects with the other drug but it's worth a try. Regards ....
I am supposed to start Raloxifene. This may cause hot flashes. If severe enough, dr will rx Effexor to treat flashes. I have been reading such negative information about the side effects of Effexor, and even worse, the are withdrawal symptoms if you have to get off of it. Is there anyone reading this that actually had to take effexor along with Raloxifene? If so, could you tell me please if you had a good, or bad experience? Thank you for any input.
A woman with ADH as well as other risk factors may have a risk that is high enough to consider medications. The medications currently FDA approved as chemoprevention for breast cancer are tamoxifen and raloxifene. Decisions to use a medication as chemoprevention would be made based on weighing the risks and benefits to the individual patient.
Aside from radiation, you can ask your doctor about other breast cancer risk reduction strategies such as that of hormonal treatment with tamoxifen or raloxifene. Other breast conditions that may increase the risk of invasive cancer would include DCIS (ductal carcinoma in situ).
Regards.
ER positivity is a good sign, since this means that the DCIS is responsive to hormonal treatment. I suggest that you discuss with your oncologist regarding additional treatments like tamoxifen or raloxifene. These two drugs are proven to further decrease the chance of the cancer recurring on the same or the other breast and I believe would be of great benefit to your mother.
Other forms of treatment post-operatively would include additional radiation therapy, or hormonal treatment with Tamoxifen or Raloxifene. All of these additional treatments are aimed to lessen the chance of recurrence as well as prevent the future development of frankly invasive cancers.
Regards.
Cancer Center physicians are participating in a clinical trial called STAR, where the effectiveness of Raloxifene is being compared to that of Tamoxifen for the prevention of breast cancer in high risk women.
Your cancer center physician will be able to discuss each of these options with you in more detail, and help to guide your treatment decision to the one most appropriate for your specific situation.
If you want further information please go to breastcancer.org the link is:
http://www.
Hi. How old are you? Are you post-menopausal? Exemestane (Aromasin) and similar drugs called aromatase inhibitors, will only work with women who have already undergone menopause. If you're in the reproductive age group, Tamoxifen is still your primary option for hormonal treatment.
I believe that you are a candidate for risk lowering strategies such as taking hormonal agents (raloxifene or tamoxifen), or surgery (mastectomy). All of these should be discussed with an oncologist or surgeon.
Regards.
Mum was diagnosed March 2005 OVCA stage 3, reoccurance 2007 and 2008, each time treated with carbo and taxol. Currently in remission. Dr put her on femera and tamoxifen but since being on tamoxifen she has had 2 DVTs in her right leg. Dr today stopped them and put her on warfrine (sorry about the spelling). Dr thinks she might have to be on this for the rest of her life. Dr also said she expects mums cancer to come back at some point but her cancer is very slow growing.
Perimenopausal breast cancer survivor on tamoxifen. After 4 months, diagnosed with AUB due to simple hyperplasia and polyps. Given a choice of hystrectomy or Ablation. Can't find any literature regarding ablation followup care since tamoxifen would be continued for 2-3 more years. What is the risk of endometrial carcinoma or other gyn issues after ablation since tamoxifen would still be providing an estrongenic effect?
Thank you for your comments... it's much appreciated!
God bless you, too!
There are some medications that are used to treat breast cancer that can be tried, though they would be used off label. These include tamoxifen (Soltamox) and raloxifene (Evista), here in the U.S. Another is Danazol. I don't know if they would be available in your country or not. Some of these drugs are quite potent and may have unwanted side effects. Be sure to discuss all of that with your doctor prior to taking them.
The other option is the surgery.
TBG excess production can be hereditary, which is X-linked dominant transmission, or it can be secondary to excess estrogens, as in pregnancy, use of oral contraceptives, hormone replacement, and medications like raloxifene or tamoxifen [4, 5]. The more highly sialylated TBG is cleared more slowly from plasma than the more positively charged TBG, because sialylation inhibits the hepatic uptake of glycoproteins.
Hi,
I can't seem to find stats anywhere on the Web for Stage I Breast Cancer, if you've had BCS but no radiation. Even stats for Tamoxifen,eg, all seem to assume you've had radiation. I had a lumpectomy; lymph nodes are clear, the tumour is only 1.1 cm, invasive tubular, as well as DCIS and one focal point of LCIS.
Hi. I'm on tamoxifen so I can't take any meds which inhibit cyp2D6 enzymes. I've been on almost ALL SSRI ( Effexor, lexapro, celexa, nortriptyline, fetzima, & viibryd) & my depression worsens with them (suicidal thoughts, etc). The only one that has helped is remeron but every time I've had to return to remeron I gain weight. I'm usually 110-112 and eat very well & workout almost everyday.
Herceptin and Tamoxifen are different drugs with entirely different actions. One does not replace the other in treatment. Tamoxifen blocks Estrogen and Herceptin deals with the over production of a protein. They are often given together. As the previous poster stated; if your tumor was Her2 positive you should definitely follow the Herceptin recommendation. Regards ...
I was recently diagnosed with DCIS, ER/PR negative and, because of extremely dense breasts, chose to have a bilateral mastectomy. I'm glad I did, because a 5mm invasive tumor was found. The tumor was Grade 1, ER/PR postive, Her-2 negative. My oncologist recommended doing nothing or, if I wanted to have some treatment, receommended tamoxifen. I've heard that Tamoxifen doesn't kill microscopic cancer cells elsewhere in the body but only inhibits their growth...
Just to add to what Lauren said regarding tamoxifen vs. other AI's, they do work differently in the body. Tamoxifen works by blocking the body's use of estrogen, whereas AI's reduce the amount of estrogen present in the body. In studies of breast cancer patients, AI's have proven to work better than tamoxifen in preventing recurrence, and there are far fewer serious side effects with AI's than with tamoxifen, too. Tamoxifen can cause blood clots, and stroke..
Hello,
I'm writing on behalf of my wife, she is 42 years old, premenopausal, and being treated (radiation therapy to come) for invasive ductal carcinoma, without any evidence of spread to nearby lymph nodes or distant sites, 1/0,8 mm tumor, low/moderate grade tumor, er+, pgr+, no family history of breast/ovarian cancer.
Although our oncologist generally treats young women more aggressively, my wife's tumor is so small he has recommended just radiotherapy.
I just saw a film Cut Poison Burn that pretty much said what the lady's dr in Puerto Rico advised: not only does the use of tamoxifen double the patient's chances of uterine cancer but taking it more than five years also increases the chances of breast cancer.
Why would you advise a lady who does not have cancer to take a drug that causes cancer?
The test also said that people with scores of 31 or higher had a 40% chance of recurrence with Tamoxifen alone, and 12% with Tamoxifen and CMF/MF. My oncologist said that the chemo drugs used in this study are old, and the outcome could even be 30% better with the new drug combos. Are there studies like this using my score and the new chemo drugs?
, locoregional or distant recurrence or contralateral breast cancer), postmenopausal women with hormone receptor–positive breast cancer should consider an AI, either as primary adjuvant therapy for 5 years or sequentially after 2 to 3 years of tamoxifen to yield a total of 5 years of adjuvant endocrine therapy. Women who discontinue initial AI therapy before 5 years should consider using tamoxifen to bring the total duration of adjuvant therapy to 5 years.
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