Raloxifene dose
Common Questions and Answers about Raloxifene dose
evista
I am supposed to start Raloxifene. This may cause hot flashes. If severe enough, dr will rx Effexor to treat flashes. I have been reading such negative information about the side effects of Effexor, and even worse, the are withdrawal symptoms if you have to get off of it. Is there anyone reading this that actually had to take effexor along with Raloxifene? If so, could you tell me please if you had a good, or bad experience? Thank you for any input.
Lymphnodes clear and had five weeks of radiation treatment. Tried Tomxifene but made me ill. Dr, recommended Raloxifene. does Raloxifene prevent the recurrance of my type of breast cancer? Marian
This discussion is related to <a href='/posts/show/261381'>Aromatase vs. Raloxifene</a>.
The medications currently FDA approved as chemoprevention for breast cancer are tamoxifen and raloxifene. Decisions to use a medication as chemoprevention would be made based on weighing the risks and benefits to the individual patient.
Aside from radiation, you can ask your doctor about other breast cancer risk reduction strategies such as that of hormonal treatment with tamoxifen or raloxifene. Other breast conditions that may increase the risk of invasive cancer would include DCIS (ductal carcinoma in situ).
Regards.
Use of Raloxifene is intended to decrease the risk of osteoporosis and to decrease the risk of invasise breast cancer or to prevent invasive breast cancer from retuning in women who have had invasive BC.
If you have questions or concerns about using it, it would be best to discuss them with the physician who prescribed it.
Best wishes...
I am not sure which medication your mother is taking, but Evista (raloxifene) can cause muscle cramps of the legs. Please have your mother make an appointment with her physician.
I have been told by Oncologist that have 5 times risk factor for breast cancer. Am on raloxifene. Last nite I noticed some dimpling on the biopsied breast abt 1" from incision scar. Just had a manual exam by the Oncologist and don't want to seem like a hypochondriac, but should I see him again. He felt nothing during manual exam, but the lump that was removed was not palpable either and only detected by mammo.
A study testing the safety of vaginal estrogen (Vagifem) for vaginal atrophy/dryness in woman on estrogen-blocking drugs such as tamoxifen
4. A study testing the safety of low dose estrogen to treat hot flahes and vaginal dryness in women on AIs
However, a search for estrogen as a treatment for ERneg BC turned up no results.
If you come across the study you referred to again, I'd really appreciate a reference or link to the information...
Other forms of treatment post-operatively would include additional radiation therapy, or hormonal treatment with Tamoxifen or Raloxifene. All of these additional treatments are aimed to lessen the chance of recurrence as well as prevent the future development of frankly invasive cancers.
Regards.
In addition, women over the age of 35 with LCIS who are at treated at the Cancer Center have access to a similar drug, Raloxifene, that may also reduce the risk of developing breast cancer. Cancer Center physicians are participating in a clinical trial called STAR, where the effectiveness of Raloxifene is being compared to that of Tamoxifen for the prevention of breast cancer in high risk women.
Osteoporosis medications like Raloxifene (Evista), alendronate (Fosomax), risendronate (Actonel) and ibandronate (Boniva) all can cause flu like symptoms in individuals that are taking them. I am not sure what medications you are on, but this could be your problem.
The hormone therapy has so many side affects. The drugs suggested for me are Arimidex or Raloxifene. Is there anyone that does not take hormone therapy and is still doing well with no recurrance?
I suggest that you discuss with your oncologist regarding additional treatments like tamoxifen or raloxifene. These two drugs are proven to further decrease the chance of the cancer recurring on the same or the other breast and I believe would be of great benefit to your mother. However, these drugs have side effects that I believe are manageable and should be discussed well with the oncologist.
Regards.
I believe that you are a candidate for risk lowering strategies such as taking hormonal agents (raloxifene or tamoxifen), or surgery (mastectomy). All of these should be discussed with an oncologist or surgeon.
Regards.
Thank you for your comments... it's much appreciated!
God bless you, too!
There are some medications that are used to treat breast cancer that can be tried, though they would be used off label. These include tamoxifen (Soltamox) and raloxifene (Evista), here in the U.S. Another is Danazol. I don't know if they would be available in your country or not. Some of these drugs are quite potent and may have unwanted side effects. Be sure to discuss all of that with your doctor prior to taking them.
The other option is the surgery.
TBG excess production can be hereditary, which is X-linked dominant transmission, or it can be secondary to excess estrogens, as in pregnancy, use of oral contraceptives, hormone replacement, and medications like raloxifene or tamoxifen [4, 5]. The more highly sialylated TBG is cleared more slowly from plasma than the more positively charged TBG, because sialylation inhibits the hepatic uptake of glycoproteins.
In reality that is the dose exposed to at the skin on the beam side, and the dose decreases with tissue depth as some of the radiation is absorbed at each level as it penetrates tissue and is therefore gone and cannot expose the deeper tissues. Many people don't understand this, but tissues actually absorb radiation, and only a small % of the radiation exits the body to form the image. Say 100% radiation enters the skin, maybe a few percent leaves on the backside.
A quarter grain is a very conservative dose, but I could be more specific if you post the lab work that led to her decision (with reference ranges from your own lab report, please).
"She is also waiting 6 weeks to recheck and then only doing TSH as she says I don't need the T3 and T4 checked anymore since surgery." Six weeks is too long when actively adjusting meds. Four weeks is plenty of time. She's dead wrong about just testing TSH.
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