I've been on Protonix
for several years, recently my dosage was upped to two 40 mg. I have nighttime reflux, never any Symptoms
during the day. All lifestyle changes made, bed elevation, not eating after 6:00pm, etc. etc. My doctor, whom I consider an able physician, has repeatedly assured me of the safety of the PPI class of drugs. Even said her 9 year old daughter was on Protonix.