Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue
growth factor expression in liver parenchymal cells.
Gressner OA, Lahme B, Siluschek M, Gressner AM.
Source
Institute of Clinical Chemistry and Pathobiochemistry, Central Laboratory, RWTH-University Hospital, Aachen, Germany. ***@****
Abstract
BACKGROUND:
Recently, we identified hepatocytes as the major cellular source of profibrogenic connective tissue growth factor (CTGF/CCN2) in the liver.