55% (6/11) of treated ducks had no measurable DHBsAg and DHBV DNA in the blood by the end of treatment and for 16 weeks after treatment was halted, no evidence of viral antigens (DHBsAg and DHBV core antigen) were found in the liver, with covalently closed circular DNA (cccDNA), the transcriptional
template of the virus, also becoming transcriptionally inactivated and reduced in copy number / hepatocyte by over 200 fold (~2.