Major side effects
of prednisolone include weight gain,facial swelling etc.Long-term side
include Cushing's syndrome, weight gain, osteoporosis, glaucoma, type II diabetes mellitus, and
depression upon withdrawal.
Symptoms of Cushing's syndrome include rapid weight gain, particularly of the trunk and
face with sparing of the limbs (central obesity), a round face often referred to as a "moon face," excess sweating.