I researched online that when the Lysodren destroys too much of the Adrenal gland, that this could happen! The overdose
throws the dog into the opposite disease, Addison's Disease. In
fact, some docs will purposely do this because Addison's is somewhat easier to deal with then Cushings. To counter the overdose of Lysodren, the vet immediately gives the dog Prednisone (spelling??). As soon as my dog got that first dose of Prednisone, she bounced back and is 100% happy and healthy!