Morphine can cause physical dependence, decreased libido, constipation
and addiction. Long term use of
Prednisolone can weaken your immune system making you prone for recurrent infections. It can cause osteoporosis, stomach ulcer, cataracts, weight gain; hirsutism etc.A drug is prescribed if the potential benefits outweigh the risks. Discuss your concerns with your attending doctor. I sincerely hope it helps.
Best wishes and regards!