Pravastatin vs atorvastatin

Common Questions and Answers about Pravastatin vs atorvastatin

pravachol

Avatar n tn Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.
Avatar f tn 9% with pravastatin (Pravachol), 14.9% with atorvastatin (Lipitor), and 18.2% with simvastatin (Zocor). And you have been on both atorvastatin (Lipitor) and pravastatin (Pravachol). Once you stopped taking statin, the pain and aches should resolve. However, for some patients, it may take up to 2 months for symptom resolution.
Avatar f tn Average incidence per 10 000 person-years for monotherapy with atorvastatin, pravastatin, or simvastatin was 0.44%" Here's the link; http://jama.ama-assn.org/content/292/21/2585.full It is extremely rare and is not associated with Zocor (Sivastatin) more than any other statin. Statins are being found to be much safer than previously thought. For instance, it has been determined that statins help increase liver function in individuals with liver disease.
Avatar f tn Coadministration with potent inhibitors of CYP450 3A4 including telaprevir may significantly increase the plasma concentrations of certain HMG-CoA reductase inhibitors and their pharmacologically active metabolites that are primarily metabolized by the isoenzyme.
Avatar f tn a randomized trial comparing the effects of atorvastatin and pravastatin on carotid intima medial thickness. 2 This was a single center, randomized clinical trial of 161 patients with mean age of 60 years and 46% with known cardiovascular disease. The effects of atorvastatin 80 mg/d and pravastatin 40 mg/d on CIMT were compared. Baseline CIMT and other characteristics were similar in both groups.
179856 tn?1333547362 After 36 weeks of treatment, the cumulative proportion of patients who reached the primary safety endpoint was lower in the pravastatin group than in the placebo group (8% vs 13%; 95% confidence interval [CI], −11.6 to 1.6; P = .1379). In fact, the mean ALT values declined from baseline in the pravastatin group, whereas the mean ALT and AST were increased from baseline in the placebo group. None of the subjects in either treatment group had an elevation of total bilirubin >2 times the ULN.
Avatar m tn Lisinopril and Carvedilol are blood pressure medications (lisinopril is an ACE inhibitor, Carvedilol is a beta blocker) and should not have any effect on your lipid profile. Both are important medications for those who have suffered a heart attack and undergone stenting. In addition to these medications, you should be on some sort of lipid medication (a "statin" such as atorvastatin, pravastatin, rosuvasatin, lovastatin, etc).
Avatar n tn Lipitor (atorvastatin), Lescol (fluvastatin), Mevacor (lovastatin), Altoprev (lovastatin extended-release), Livalo (pitavastatin), Pravachol (pravastatin), Crestor (rosuvastatin), and Zocor (simvastatin). Combination products include: Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe). The new labels will warn patients about: Memory loss and mental confusion.
976897 tn?1379167602 If only I could get results like that. Even with the Tricor and Pravastatin my Trigs were still around 325. ***sigh*** Congenital defect.
Avatar m tn It has been studied as noted by the excerpt from the NIH below. There has been a small plaque regression with LDL levels below 70, increased HDL, statin therapy and aerobic exercise; "BACKGROUND: The purpose of this study was to explore the effect of lifestyle modification, mainly daily aerobic exercise, on coronary atherosclerosis in patients with coronary artery disease (CAD).
Avatar f tn Can someone explain what, if any, evidence there for a switch from simvastatin to pravastatin? My husband's doctor said there is new evidence that simvastatin may be detrimental. Unfortunately, my husband did not quiz him further. He already has one stent in a narrow back artery but he has brought his cholesterol down considerably with the statins.
Business man2 All Moderators and Dr. Murphy: Please pass along to management and Doctor/Expert Murphy what a NEED this forum meets!!! It gives people like me the chance to get another opinion regarding "nagging" questions that aren't quite "settled" in our minds. Dr.
Avatar m tn [12, 76–78] In a large randomised, prospective, placebo-controlled trial with high-dose pravastatin (which, in particular, does not undergo P450 metabolism) in hypercholesterolaemic patients with compensated liver disease due to mostly non-alcoholic steatohepatitis or HCV, the cumulative risk of doubling an elevated baseline ALT value over 36 weeks was in fact lower in the pravastatin-treated group compared with untreated controls (7.5% vs. 12.5%).
Avatar f tn //www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.
Avatar n tn I was on 40mg of Pravastatin and now am on 80mg. Is my doc just being aggressive? Or is there another reason for the big increase? I welcome any speculations.
Avatar f tn I am a 39 year old, female. I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.
Avatar m tn m still trying to get a clarification. Anyway, the cardiologist put me on Amlodopine and Pravastatin. Now, on a daily basis it seems, my heart rate increases and beats at 90-115 bpm (normally in the mid 70s). At the same time, I've started on a vegetarian diet to try to lower my cholesterol. To try to make sure I get enough protein, I am using a protein drink (10-14 gr protein each). I drink 1-2 of these per day.
Avatar n tn It seems that the main problem was with fenofibrate and pravastatin. The level was pravastatin was greatly increased. But newer info with other statins shows no danger. Atorvastatin serum levels were actually decreased. Jack is very correct that any individual's response can vary a lot from the norm. > Any other natural suggestions on lowering [TG]? I've seen studies that low carb works best, but low Glycemic Index is not that far behind.
Avatar f tn I was put on Pravastatin about 9 weeks ago as my cholesterol had gone from 190 to 225 from the previous year. I have a family history of heart disease (my father passed away after a second heart attack at 53). I was diagnosed with hypothyroidism 2 years ago and was placed on Levoxyl (75mg) and my levels have remained normal. I went to have my cholesterol checked after taking the pravastatin for 9 weeks.
Avatar n tn I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.
Avatar n tn It is easy to find information regarding drug-drug interactions for omeprazole (Prilosec) and atorvastatin (Lipitor). The omeprazole appears to increase the bioavailability of the statin, increasing the risk of side effects. Does this mean that the interaction is like taking a higher dose of the statin, which would provide benefit for someone like me who only takes a low dose (10mg atorvastatin daily) and has no statin tolerance issues?
Avatar m tn Is it safe to take Levothyroxine at the same time as Pravastatin? Also, 2 months ago, I started to take my Levothyroxine at bedtime instead of in the morning as it is more convenient. and after a recent bloodtest my GP has reduced my Thyroxine to 75mcg instead of 100mcg. Could taking it at bedtime be the reason for this reduction? I will obviously ask my GP about this on my next visit to the surgery but would be grateful for any advice.