Pravastatin and simvastatin
Common Questions and Answers about Pravastatin and simvastatin
pravachol
Both simvastatin and pravastatin have the same side effect profile, but it does depend on the individual as to whether one would cause more issues than the other."
The only negative I have read about Simvastatin in recent times is a study that showed high doses of simvastatin of 80 mg puts a patient at a greater risk for side effects including muscle damage. Most doctors have backed off of the 80 mg dosage as a result.
“If you are unaware that a patient is on simvastatin and you give either boceprevir or telaprevir, the simvastatin level in the blood can go high and patients can develop muscle breakdown,” said Dr. Jensen.
http://www.idse.net//ViewArticle.aspx?
s production of cytochrome P450, I am wondering about switching from simvastatin to pravastatin. That would allow me to try CBD, which appears to have minimal side-effects. I also wouldn't mind getting more than a few hours of sleep per night. That said, am I taking a risk by switching statins after three decades? I haven't been able to find any significant and update research that covers this situations. Thank you.
It seems that the main problem was with fenofibrate and pravastatin. The level was pravastatin was greatly increased. But newer info with other statins shows no danger. Atorvastatin serum levels were actually decreased.
Jack is very correct that any individual's response can vary a lot from the norm.
> Any other natural suggestions on lowering [TG]?
I've seen studies that low carb works best, but low Glycemic Index is not that far behind.
Advicor (lovastatin/niacin extended-release), Simcor (simvastatin/niacin extended-release), and Vytorin (simvastatin/ezetimibe).
Lisinipril is $4/month and $10 for 90 days at WalMart and many other pharmacies that have the $4 precription plan. You pay out of pocket. Simvastatin isn't on that list, but lovastatin and pravastatin are, if your doctor feels like you could try substituting one of those. Metoprolol isn't on the $4/month plan, but atenolol is. Again, maybe your doctor would be okay with changing you from metoprolol to atenolol. It's worth talking to the doc about.
Average incidence per 10 000 person-years for monotherapy with atorvastatin, pravastatin, or simvastatin was 0.44%"
Here's the link;
http://jama.ama-assn.org/content/292/21/2585.full
It is extremely rare and is not associated with Zocor (Sivastatin) more than any other statin. Statins are being found to be much safer than previously thought. For instance, it has been determined that statins help increase liver function in individuals with liver disease.
Here is an update as of Aug. 30.
I went back to the Dr.'s for a plan-of-action for the high cholesterol numbers. We decided to try Simvastatin 20mg's and I also will be adding CoQ-10 with that (my suggestion). I will be having another reading done in December to see if it brings the numbers down. He also suggested I have a Coronary Calcium Score CT done.
I had the Coronary Calcium test done the next day and received the findings today. The Total Agatston Score is 0.
9% with pravastatin (Pravachol), 14.9% with atorvastatin (Lipitor), and 18.2% with simvastatin (Zocor). And you have been on both atorvastatin (Lipitor) and pravastatin (Pravachol).
Once you stopped taking statin, the pain and aches should resolve. However, for some patients, it may take up to 2 months for symptom resolution.
t read anything that says the Zocor was responsible, just conjecture that it may be based on some Internet research. Zocor which is merely simvastatin is very safe and the incidence of side effects very low, but some will be affected differently than others.
//www.drugs.com/sfx/pravastatin-side-effects.html#consumer_Pravastatin
Have you discussed this with your doctor? If you take other drugs and/or supplements check with your pharmacist regarding drug interactions.
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good article about the use of fluvastatin with hcv, as regards hbv simvastatin and lovastatin are the only statins i have seen studied on hbv (among the two sim at 80mg has the strongest effect)
Two recent trials have compared the clinical outcomes of intensive lipid lowering with atorvastatin 80 mg/day and standard lowering with pravastatin 40 mg/day. In the Pravastatin or Atorvastatin Evaluation and Infection Therapy (PROVE IT) trial, patients with acute coronary artery syndromes were enrolled, and pravastatin lowered the low-density lipoprotein (LDL)-cholesterol to 2.46 mmol/l, whereas atorvastatin lowered it to 1.60 mmol/l.
I recently was prescripbed pravastatin and I notice a higher number when I test after a night of fasting in my Blood Glucose. Is there a posibility that could cause the rise.
59 yo white male. 1 year post MI with two stents in my RCA. I am active and with high a normal BMI of 25 No problem walking a fast mile or with light exercise. My LVEF was 50% right after MI and 45% 2 months later. due for another echo in 2 months. my lipids are under control - LDL < 70 and TC < 140, with or without the 10 mg pravastatin I am prescribed as I eat mostly a quality plant based diet, low in fats and simple carbs..
My question has to do with drugs.
I was on 40mg of Pravastatin and now am on 80mg. Is my doc just being aggressive? Or is there another reason for the big increase? I welcome any speculations.
t seem overly concerned. He said I could go off the pravastatin and see how my numbers were with diet and exercise alone. I have been on a good routine with proper diet and regular exercise and I am at the low end of my healthy weight. I have low to normal blood pressure. Anyway, searching for info on this today, I can't find anyone with such low LDL levels but the term "dangerously low" pops up for women with HDL less than 40.
m still trying to get a clarification. Anyway, the cardiologist put me on Amlodopine and Pravastatin. Now, on a daily basis it seems, my heart rate increases and beats at 90-115 bpm (normally in the mid 70s).
At the same time, I've started on a vegetarian diet to try to lower my cholesterol. To try to make sure I get enough protein, I am using a protein drink (10-14 gr protein each). I drink 1-2 of these per day.
It has dropped my LDL to 39-45 range and blood glucose ranges from 105-111 fasting. A1c 5.1 - 5.3. Prior to the statin I was below 100. I am not overweight, exercise consistently and eat very healthy. So the statin is the culprit. I am wondering if being stricter on carb intake and supplementing with Berberine will help? Or has anyone had better outcomes with other statins like livalo or pravastatin?
I quit taking the simvastatin last tuesday, and by friday I looked perfectly normal with no steroid cream......
Thanks again for all the help!
I use simvastatin to lower the cholesterol and lisinopril to lower the bp. The lisinopril works w/o the simvastatin and v.v.
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