I would become nauseous each time I took it at bedtime and often this would continue the following morning. Within two weeks, I had joint paint, nausea, fatigue, nosebleeds, bruising, and
. I took 165mg 80% silymarin for 14 days and this helped. 5 days after stopping silymarin, my symptoms returned in full. I then had a midnight attack of acute RUQ pain with nausea/vomiting that landed me in the ER.