plavix and nexium study

17, 2009 - The FDA today warned patients not to combine Plavix with Nexium, Prilosec, and nine other drugs -- including Prozac and Tagamet. The drugs may make the anti-clotting drug Plavix dangerously less effective, the FDA says. They block an enzyme in the body that turns the drug into its active form. Plavix is the second most-prescribed drug in the world.

I am on plavix also and was taking nexium for gerd. My cardiologist told me to go off the nexium because the FDA has found that the nexium or any of the PPI's inhibits the plavix from working properly. I am now on pepcid instead of nexium. I am curious to find out if your cardio's had mentioned this to you. Protonix is in the same group of PPI's as nexium. Google plavix and ppi's or go on the FDA website. You will read a lot about the two meds. Just for your info.

Ask your Cardio or GI doc. They should be able to give you the infor you need. I am taking plavix and was on nexium. Had to go off it because of the FDA findings. Am now on pepcid You can also look on the FDA website for more info on that. Good luck.

I had angioplasty in 2001 and had a stent implant. My cardiologist prescribed Plavix and 81 mg aspirin daily among the other medications (beta blocker, ACE inhibitor, statin). I have recently moved to a new city and have not found a new cardiologist yet but family physician suggested that Plavix could be discontinued as the guidelines have changed and no long recommended after 12 months post stent implant. Suggestions please?

My cardio took me off the nexium and put me on pepcid. Google plavix and nexium to get more info on this subject or go to the FDA website.

s Journal of the American Medical Association (JAMA) reports a two-fold increase in death and heart attack in the 90 days after heart patients completed their prescribed course of medical therapy with clopidogrel (Plavix). The increased risk occurred whether or not patients had received stents and was similar for all durations of clopidogrel therapy studied: from less than six months to more than a year.

It might be necessary to increase the Nexium dose, but from my experience, this is a very minor issue. The need to take Plavix trumps the Nexium issue. Plavix and aspirin are essential to keep your stents from plugging up again. It sounds like your hospital doesn't have a good program in place for education after an MI and cath. I work a day a week at our hospital as a Cardiac Navigator, as I've had MI's, eight stents, a pacer and bypass surgery and still standing.

He has recently had to put me back on Nexium for severe acid reflux, but told me to take Plavix in the morn. and Nexium at night. Have to have some blood work done in 1 month.

I am on my second DES in my LAD-first a cypher stent that had a proximal occlusion at the leading edge of the stent after two years,8 months on Plavix and con't on asa-325.

My heart Dr will not let me go off the plavix and my surgeon will not do the surgery while on plavix. What happens in a situation like this?. I am between a rock and a hard place. If neither Dr gives in what do I do? If I have an attack and end up in the ER wouldn't they have to do emergency sugery?. Does this mean that anyone on plavix can never have surgery unless it's an ermergency. What is your opinion on going off plavix temporarily for surgery. I would welcome anyones advice.

The mixture of Metroprolol, Ezitrol, Lipitor, Ramipril, Isordil, Plavix, Nexium and Aspro and now Coralan leaves me feeling quite week and lathargic and always very tired. My BP is steady at around 100/60, my cholesterol is below 4. I did used to walk about 2km a day before I started Coralan even though I got angina, but now I feel I just dont have the energy to do the walk to see if I still get angina. Not sure what yer answer might be but thought Id write this down anyway.

Had multiple stents (4) placed four (4) years ago, two in LAD with no side effects and good nuclear and stress test results over this period. Am currently taking Plavix/Aspirin/Coreg/Altace. Need arthroscopic repair on knee but concerned over cessating of Plavix. One cardiologist recommended ending Plavix entirely, second (same practice) would rather wait for a large study about to be completed. Suggestions?

He went into a clinical study that put stents into these arteries (stents not yet approved for brain) anyhow, he is on both plavix and asprin. But like Tim said you should ask your Dr.

I have a problem with thin skin that will tear easily, my cholesterol is under control and he suggests I simply eat salmon at least once a week, easy to to where I live. Both Plavix and fish oil have been withdrawn. I try and eat salmon I catch or wild, troll-caught salmon, and avoid farm-raised salmon.

I was told to take Nexium and contact a urologist. Four days later I went to my local doc because the pain continued and was still severe(burning, tightness). My doc did bloodwork and came running in the room with nitro and a handful of aspirin for me to chew, and immediately sent me to the nearest Cardiac Care Unit via ambulance. After tests, the cardiologist concluded a 98 percent blockage in my right artery and almost 65 percent blockage in the left.

I have been reading posts were plavix is given for a lifetime, etc. and I find no published medical study or literature that supports giving plavix other than what I have stated. Does your doctor provide a reason? You have an option to get an explanation from your doctor and/or get a second opinion...I know of no reason other than a monetary motive, but I have an open mind for relevant information. Take care, Ken.

What I would recommend you do is call whoever did your last angioplasty in 2008 because they know your coronary arteries the best and ask if you can go off Plavix. I think you would probably be ok going off Plavix since it has been 3 years from your last intervention and that was only ballooning but again there is a small risk of restenosis of your stents.

I went through a period of very aggressive CAD, and my Cardiologist kept me on Plavix for almost five years, so I took Plavix with both types of stents during that period. Yes, I did have surgery for a bowel obstruction when taking Plavix, and indeed, it was a huge issue. I did have to have transfusions and my Cardiologist was part of the bowel surgery team, but I'm still standing, today I worked out at the fitness center.

I also have eight stents, they are in all three major heart arteries, seven of them were inserted within eighteen months about six years ago. Half of my stents are drug-elluting, half are bare-metal. I was also told initially I would be on Plavix the rest of my life. However, I really worked hard to change my risk factors... of course I didn't smoke, I quit eating red meat, lost a great deal of weight, took the good drugs recommended by my doctor, and exercised daily.

The clinically important adverse reactions observed in trials comparing Plavix plus aspirin to placebo plus aspirin and trials comparing Plavix alone to aspirin alone are discussed below. Bleeding CURE In CURE, Plavix use with aspirin was associated with an increase in major bleeding (primarily gastrointestinal and at puncture sites) compared to placebo with aspirin. The incidence of intracranial hemorrhage (0.1%) and fatal bleeding (0.2%) were the same in both groups.

The usual protocol for the drug eluding stents is dual therapy of aspirin and plavix for a year. The reason for plavix is that DES has a tendency to clot when compared to bare metal stents, and less a problem for restenosis (overgrowth of tissue within the lumen). After a year medical consensus is to discontinue plavix as there is less risk for clots, but continue with aspirin for a lifetime. There may be some individuals that have a higher risk for clots so plavix may continued indefinitely.

She was on acid blockers for 25 years (tagament for 20 years, nexium for 5 years and also took gaviscon for 10 years). I took my mother off nexium and gaviscon cold turkey and started digestive enzyme supplements and betaine HCI with pepsin supplements in their place. She never got worse only better. She no longer suffers GERD, LPR and is 95% improved with gastritis. If you don't want to go cold turkey you could try taking digestive enzyme supplements and wean off nexium more slowly.

Apparently, OP experiences other problems believed to be associated with plavix and that should also be a consideration for him. I discontinued plavix after a year or so and my wallet is happy.

I hope I can shed some light on this for you from my personal experience, it was a concern of mine as well. I'm also 67 years old but try to stay young physically and mentally. When I started getting blockages, they came regular intervals over a three year period, and have eight of them, along with several heart attacks. As a result, I took Plavix for four years, along with 81mg of aspirin.

i saw this guy floydd wright on youtube who says do not take nexium if you have hep c . has anyone heard of nexium being dangerous to induce hep c ?

I have read so often that you should not take Plavix and aspirin, but it seems to also be common to prescribe both plavix and aspirin in certain situations. I am worried and confused. Thanks.

EF= 65% -Consider cardiac catherization I was wondering if a stent is 100% necessary, or could my father just take Plavix or Aspirin without stenting? Also, being my father has a good exercise capacity and an EF of 65%, if he does receive stents- how long do you think he’ll be on medicine for?

The American Dental Association has agreed with the American Heart Association and the AMA, that there are no dental procedures that require the patient to stop Plavix. I read this yesterday, and the article mentioned that much to their dismay, cardiologist were still hearing from their patients that some nutty dentists were still asking them to stop Plavix for a procedure.

Plavix and nexium study

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