Pioglitazone and osteoporosis

Common Questions and Answers about Pioglitazone and osteoporosis

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These findings suggested that treatment with PPARg agonists may provide a new upstream treatment strategy for patients with LPP and frontal fibrosing alopecia. Pioglitazone and rosiglitazone are glitazones and PPARg agonists that are FDAapproved and used widely to treat type 2 diabetes mellitus as well as atopic dermatitis. Pioglitazone was successful in a 47 year-old male patient with active and symptomatic LPP who had failed all treatments.
Ulcerative colitis is linked to overgrowth with pathogenic microbes, the same as Crohn's disease, osteoporosis and ankylosing spondylitis. In ankylosing spondylitis the vertebra of the spine fuse together causing stiffness and pain. Other joints may in time become affected. Klebsiella, another type of pathogenic bacteria, produces a molecule that is similar to a tissue type found in people with this disease.
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