Phenytoin serum levels

Common Questions and Answers about Phenytoin serum levels

dilantin

Avatar f tn Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..." It however says that initiation of Folic acid and phenytoin together is beneficial. Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
Avatar n tn Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body. Hence, every person react differently to same drug.
Avatar f tn There may be wide interpatient variability in phenytoin serum levels with equivalent dosages. Patients with unusually low levels may be noncompliant or hypermetabolizers of phenytoin.
4309115 tn?1357606283 However the usefulness of measurement of serum GGT is limited by its lack of specificity. Raised GGT levels have been reported in a variety of clinical conditions including (1): pancreatic disease myocardial infarction chronic obstructive pulmonary disease renal failure diabetes obesity alcoholism Drugs such as phenytoin and barbiturates may cause high GGT levels (2).
Avatar m tn In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780] Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.
5268376 tn?1406179712 If you seriously had any concern that the arrhythmia could be life threatening, go to the Emergency Room. Also consider phoning your family doctor and explaining your concern. I looked at Zithromax side effects, they vary by the dosage, single or multiple doses, doses in combination with another drug, and are listed as pre-marketing trials and post-marketing reports. Rhythm issues were reported less than 1% of the time in pre-marketing trials, and also in post-marketing reports.
Avatar n tn Combining fluoxetine or paroxetine with phenytoin can also lead to increased phenytoin side effects and reduce blood levels of paroxetine. You really need to discuss the potential drug interactions with your own doctor.
Avatar m tn An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes. Whereas if you are a chronic alcoholic, the phenytoin levels may be lower than expected and can cause seizures. I suggest you consult with your neurologist in this regard. Hope this information helps. Take care.
Avatar n tn Such medications as carbamazepine and phenytoin have been shown to displace thyroxine from plasma protein-binding sites and potentially increase its clearance. Free thyroxine (T4) and triiodothyronine (T3) will be increased, while serum T4 and T3 levels will be decreased. Authors have speculated, therefore, that thyroid-stimulating hormone should be followed to determine if a patient on anticonvulsants has normal thyroid levels (JAMA. 1996;275:1495-1498).
Avatar f tn I would recommend testing vitamin B12 and folate and a full iron panel (not just iron serum) to start with. Just to note, vitamin B12 serum reference range is extremely low in almost all countries so deficiency symptoms are well documented to occur in low normal ranges. Europe and Japan have risen the lowest acceptable range to around the 550pg/mL mark which is a vast difference to 200pg/mL which is found on most labs!
Avatar f tn I was then lowered to 200mg which I could handle quite well. My levels were checked in Feb.08 and the levels were low at 29, my Dr. raised the dose to 250mg wich moved my levels to 55. which she said was good. In a short time of being on that I started to get the same side affects as on the 300mg. My Dr. told me to go back to the 200mg and she would have to talk to my Neurologist, I just had blood work done again and my phenytoin level come back at 2. How is that possible?
Avatar n tn can prozac and trazadone cause false positive or elevate serum blood alchol levels
Avatar n tn Hi there. Since your frequency of seizures has increased you need to have a fresh evaluation of your neurological function clinically, with a recent MRI brain and an EEG. The antiepileptic drugs need to be checked for a dosage modulation, assessment of adverse effects due to chronic usage over years like megaloblastic anemia, gingival hypertrophu and osteomalacia with phenytoin. Take care.
Avatar f tn Does prednisone effect dilantin and lamictal levels? I've been on dilantin and lamictal for over 5 years for seizures. I'm being tested for autoimmune hepatitis, I just had a liver biopsy. I don't want to take a chance on having a seizure.
Avatar m tn I believe that the benefits pf statins outweigh the risks and have altered my eating lifestyle so to nearly exclude carbohydrates. This has enabled me to continue statin regime while keeping my fasting blood glucose levels at acceptaptable unmedicated levels. My wife on the other hand continues to take Metformin while on the statin drug.
1291453 tn?1272143404 You should tell your doctor if you experience any of these symptoms while taking phenytoin, so that your blood level of phenytoin can be measured and your dose reduced if necessary. " Also, he has had a major surgery, and will need time to recover. However, any changes need to be reported to the doctor.
Avatar m tn Almost any medication, including OTC medications, CAM, and substances of abuse, has the potential to elevate serum aminotransferase levels. Common causes include nonsteroidal anti-inflammatory drugs, antibiotics, statins (cholesterol medications), antiepileptics (seizure medications), and antituberculous medications. Then, the physician can prove the medication is the cause by stopping the medication and observing return of the enzyme levels to normal.
Avatar f tn I have had some on going health problems for many months now. I have had many strange things come up in lab work, on MRI's, etc. Recently It was discovered that serum copper levels are very high. 250,normal is 70-150. could this have anything to do with my thyroid? My TSH was checked in Feb. (2.75-normal),and an ultrasound of my thyroid revealed a small nodule on the left lobe. My father is currently battling thyroid cancer.
Avatar f tn csf fluid), but now I found out that my serum copper levels are high-250(normal range70-150). I do not have any hepatic symptoms. My ceruoplasm levels were normal, and I do not eat a copper rich diet. Does anyone have any ideas? I go back to the doc on Tues, but I wanted a heads up. Thank you!
Avatar m tn Recent bloods show low serum iron levels, normal ferritin levels, normal red blood count and high in inflammation. What could be causing this? GP thinks it's connected to ETAP and intestine not absorbing iron, getting enough blood. Being referred to specialist. Not sure what all this means.
Avatar f tn My first question is regarding the HDL and LDL levels...is 76 too high for HDL? Should HDL number be higher than LDL? Also l would like to know a little more about albumin (what it is and average levels). Glucose was 95. Thanks in advance for whatever help you may give me. Greatly appreciated!
Avatar f tn Granulosa-cell tumors produce inhibin and its serum levels reflect the the tumor burden. Measurement of inhibin can be used as a marker for primary as well as recurrent granulosa cell tumor. The recent availability of markers of ovarian stroma, including melan-A and inhibin-alpha, has provided a means for the positive identification of ovarian stromal tumors, which can manifest in a myriad of histological appearances.
Avatar n tn Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..