Phenytoin lab values
Common Questions and Answers about Phenytoin lab values
dilantin
My question is, are there any specific lab values that represent ascites and if the “causes” of ascites specifically are getting better? I understand the cirrhosis is the cause but are there certain LAB values that represent or can be used to judge ascites and see if the TIPS will perhaps work again?
That's not an easy question to answer since reference ranges for thyroid lab tests are very flawed. TSH is a pituitary hormone, and as such is a screening test at best for asymptomatic individuals. Typically, individuals who are hyper have TSH less-than 0.3, and hypos have TSH greater-than 3.0. However there are esoteric thyroid problems that don't conform to that rule and can actually reverse it.
Hi there. Since your frequency of seizures has increased you need to have a fresh evaluation of your neurological function clinically, with a recent MRI brain and an EEG. The antiepileptic drugs need to be checked for a dosage modulation, assessment of adverse effects due to chronic usage over years like megaloblastic anemia, gingival hypertrophu and osteomalacia with phenytoin.
Take care.
Yes, bleeding can cause a drop in CBC values and once the bleeding stops these values improve. Low triglycerides with normal or high cholesterol can be due to poor eating habits, hyperthyroidism, malabsorption syndromes (including Crohn’s and most likely cause in your case), as a side effect of certain drugs (like nicotinic acid, clofibrate), etc.
sorry but normal alt values has been changed since years on european and US guidelines and of course on all studies, normal alt is 30 for men and 19 for women
studies on liver related deaths suggest even lower alt at 15 for both men and women but since diet on most western countries is rubbish such low values can t be used because most population has higher values due to chemicals in food and type of diet
as to problems with bones it is well known they are due to low vitamin d 25 oh levels whi
t tested for that. The values they gave were 1.19 igm and 0.16 igg. These results were taken from a blood test of some sort. From what I have been reading on some of the boards it seems that this test is unreliable. Is that so? What do these values mean? Why in the world would these people tell us she has herpes if that's not the case? Since these values are so low does that indicate a possible false positive? Or does it just mean that her exposure was too recent to tell?
Hello, I just got some lab results back. I found out I have Hep C back in 1999. Had a liver biopsy it wasn't too bad and have been tracking lab values since. I recently got these labs back and am wondering if anyone can tell me if I should be alarmed and what to do next. I am just switching from Military health care to Civilian Health care. I have ben feeling like total ****.
Genotype 1b
ast194
alt 274
HCV ab 34.
Yes there are issues that can complicate diagnosis, but with hypo symptoms and those test results for Free T3 and Free T4, it is pretty clear that your thyroid hormones are too low in their ranges. I say ranges, because I am assuming that the reference ranges shown for those tests would be similar to those I see quite often. The ranges are far too broad, since they were established erroneously and have not been corrected like done for TSH over 10 years ago.
In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780]
Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.
Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..."
It however says that initiation of Folic acid and phenytoin together is beneficial.
Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
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