phenytoin bradycardia

Last year he had a grand mal seizure - with no apparent cause - he was put on to phenytoin for 6 months but as it stayed below theraputic levels and he had no sign of further seizures he was weened off it. Over the last 6 weeks he has become tired, miserable, sad, angry, withdrawing from activities, complaining of dizzy spells and headaches.... because of his autism his pain threshold is crazy ( he had a huge hernia and felt no pain... he dislocates his knee cap by choice with no pain)...

In a small study, phenytoin-induced seizures occurred most often in patients with serum phenytoin concentrations of 50 mcg/ml or higher.[393] Peripheral neuropathy, usually occurring weeks to months after drug initiation, has also been reported in patients receiving phenytoin. A single case report describes the onset of neuropathy within a few hours of drug administration.[9780] Adverse GI effects of phenytoin therapy include nausea/vomiting, constipation, abdominal pain, and anorexia.

Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..." It however says that initiation of Folic acid and phenytoin together is beneficial. Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.

Combining fluoxetine or paroxetine with phenytoin can also lead to increased phenytoin side effects and reduce blood levels of paroxetine. You really need to discuss the potential drug interactions with your own doctor.

Hi everyone, I'm new to this community. My neurologist just informed me that Osteoporosis and shrinkage of the Cerebellum are very serious side effects for long term users of Dilantin. Does anyone know more about this? I've been taking 500mg of Dilantin for over 30 years since I was a teenager, and now I'm terribly worried. Not one of the neurologists had mentioned anything about this over the years, and now at 46, I've learned that I may have severe osteoporosis.

You should tell your doctor if you experience any of these symptoms while taking phenytoin, so that your blood level of phenytoin can be measured and your dose reduced if necessary. " Also, he has had a major surgery, and will need time to recover. However, any changes need to be reported to the doctor.

Moban® brand of molindone hydrochloride contains calcium ions which interfere with the absorption of phenytoin. Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems”. Taken from http://www.rxlist.com/cgi/generic/phenyt_od.htm Our population is divided into 4 type of metabolizers ranging from rapid to slow metabolizers depending upon the speed of elimination of drug from body.

Thank you for your question, you are relatively fine with Phenytoin and the seizure episodes in a form of lack of speech are the residue of a generalized type seizure. I don’t have a full description of your consciousness during the lack of speech episodes to decide whether this start is a partial epilepsy which can continue in a generalized or it is a generalized one from the first moment..

Hello AB, welcome to the medhelp forum. Phenytoin can cause certain side effects like dizziness and mental confusion. Some people may also manifest incoordinate movements. Weight gain is not a documented side effect. It could be related to your alcohol consumption or wrong dietary habits and lack of exercise. An occasional one or two drink may be fine but moderate or large amount can cause significant increases in blood levels of phenytoin due to induction of hepatic enzymes.

During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.

I totally forgot to tell you that he is on Phenytoin 100mg once daily. Can this be continued and taken for a long period of time? Thank you doctor once again for your immediate reply.

http://www.webmd.com/heart-disease/tc/bradycardia-slow-heart-rate-overview#1 Unfortunately, acupuncture has no helpful effect on bradycardia.

Addition of other antiepileptic drugs like phenytoin,lamotrigene and sedatives will be helpful for controll of his night symptoms.

Would bradycardia be a help or a hindrance with regards to mitral regurgitation? bradycardia between 40-50 bpm awake but resting,lower when sleeping. MR of unknown severity....

Is my bradycardia normal? Am I at risk of getting a worse (symptomatic) bradycardia? I never smoked, I never did drugs, I rarely drink alcohol. I weight around 154 lbs and I'm around 5.

ve heard of that might help with the itch are trying the over the counter antihistamines or antihistamine hydroxyzine (Atarax), anticonvulsants (e.g. gabapentin, carbamazepine, phenytoin), antidepressants (e.g. amitriptyline, paroxetine, mirtazapine), and even Pregabelin (Lyrica)....

A few weeks ago I woke up with yellow crust on the corner of my lips and it went away in 2 days, and today I woke up and it's in the exact same spot again except a little more then before. It doesn't hurt or itch, it feels like my lips are very very dry. I don't smoke, I have grandmal seizures and my medication is phenytoin and kepra but I didn't read anywhere that would be a side effect so I'm worried this could be a STD or something.

I just got my results from a cardiac event monitor. I have tachy-brady syndrome. Can anyone please explain these terms. Bradycardia with SVPB's? Ectopic atrial rhythm? Sinus bradycardia with junctional beats? Any info would be so helpful.

I also have "bradycardia" with a resting HR of 48. My BP is also lower, in the 96/54 range. I have attributed mine to being a cyclist and runner, altho that has never been quantified. In terms of sleep apnea, I do not know if that would be the cause. If you have had the apnea for awhile, then I would be hesitant to link the 2 since it sounds like your HR just recently dropped. Your attempt to stop smoking (congrats!

How dangerous is this condition my wife newly diagnosed bradycardia via holter monitor low was 44bpm high was 132bpm ive done some searching but im scared for my wife we just lost insurance and the county hospital cant see her till mid december any opinions would be greatly appreciated...

d him for football this year but says he wants all test done again next year before he enters highschool. He also wrote down Bradycardia on the physical. The Cardiologist never said that before. I want to know if you think it's ok to let him play this year or should I have the test done this year. I'd never forgive myself if something happened.

I developed severe bardycardia (36 bpm), which is what eventually led to the discovery of the lymes. I was wondering if anyone has had the severe bradycardia and after treatment for lymes the bradycardia is completely gone? I am currently on week 5 of the antibiotics and my heart rate is now in the mid to upper 50's at rest, a great improvement. I have been here for a couple weeks and was wondering if it will continue to improve as i have 7 more weeks on the antibiotics.

I am a 44 year old male that has had 13 orthopedic surgeries in the last two years. The most recent was an ankle reconstruction that has had me in bed since 2/18/09. I have high blood pressure and have been on Cardizem CD 240 and Hyzaar 100/12.5 for about 17 years. I also have mitral valve prolapse. My resting heart rate has always been around 60 even before medication as I was a weightlifter and football player when I was young.

I have bradycardia! My hart rate has been rcorded numerouis times while resting at 28bph. I sometimes get light headed especially when straightening up from bending over. My normal heart rate while sitting is around 50. Do I have a problem which should be addresses or is my heart just relaxed?

Phenytoin bradycardia

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