Phenytoin and liver function
Common Questions and Answers about Phenytoin and liver function
dilantin
thought it went away but apparently did not and grew. had complete CBC in june and in september and were both normal. had mammo and ultrasound. radiologist said not breast or lung cancer. he did find also enlarged lymph nodes under left armpit. then saw surgeon and she also found enlarged lymph nodes by groin. I have zero symptoms of lymphoma. all drs are thinking it can be that. what do you think. all enlarged lymph nodes are on my left side. I have zero history of cancer in my family.
well the problem is that today it increased to 4.5 ! and we found out that the left kidny is smaller than the other ! n all the other test results are just fine !!
This reaction is generally confined to the extremities but can affect the trunk and face and may be irreversible. Severe dermatologic reactions to phenytoin are infrequent. Some evidence, however, suggests that erythema multiforme is more likely in patients who undergo radiation therapy while receiving phenytoin.[22]
Lupus-like symptoms have been described for phenytoin. Whether phenytoin administration will exacerbate preexisting idiopathic systemic lupus erythematosus (SLE) is unclear.
"Can you get Cirrhosis of the liver with painkiller and sleeping tablet addiction?? "
Painkillers and sleeping tablets will not cause Cirrhosis of the liver. Other medications like certain anti-fungals can. Certain medications can cause further harm if you already have some form of liver disease.
In Total liver Function Laboratory Blood Test results (Alanine Amino Transferase Serum) conducted for Total Liver Function shows presence of low ALT or low SGPT levels of 14 . This result is quite below the range limits specified in the lab. test report which is between 17-63 .. Please intimate what will happen if it further reduces in the ALT levels and how to increase the ALT levels or how to come out from this problem .
* Is it relates to early death of a person ?.
I had an aunt who died from liver cancer and her liver function tests were normal until the end stages. However, it is common to have cysts in the liver and fatty areas that aren't a problem. When I was dx they found a hemangioma in my liver and another cyst and there were two cysts in my kidneys. Before my surgery, I thought this must indicate cancer had spread there only to find out that most of us do have some sort of cyst congenitally or as we age. My dr.
What supplements or other over the counter meds would you suggest to help improve my
I'm a 48 yr old black female who began having seizures 7-8 yrs ago. they have increased to about 1 time a week. I'm taking 750 mg of Keppra and Dilantin 100mg 2 x a day.
Hi,
Citilin(CDP Choline) is used in acute stroke and head trauma cases for proper neuronal function as a protection to brain.Usually its given for not more than 1-3 months.Dose is 500-2000 mg per day.For TIA and stroke with hypertension the drugs which your father is using are right ones with proper doses.Please keep updating for further information.
During those times I had not yet been diagnosed and was able to go back to life like normal, however after the diagnosis and being on phenytoin and switching to oxcarbazepine i am feeling awful. Dizzy, nauseated, moody, extremely tired, severe headaches that come and go. All i get from my Neurologist is these are side effects that will eventually go away. Because i never know when these symptoms will come on too strong I have missed a lot of days at work during my probation period.
Hello everyone. So a little backstory first.
I was diagnosed with Graves disease back in 2013-2014. I was put on the methimazole + beta blocker treatment. I went into remission around 2016, when all my labs were normal. So I stopped the meds.
Then, March of 2018, Graves was back with a vengeance. All the telltale signs were back, the excessive heat and heart palpitations, I went back to the doctor and back on drug treatment. This time, however, the meds doesn't work whatsoever.
I went ahead and got a hepatic function panel done last week. i got results back and it shows my ALT level at 57. on the paper work i got from the lab it shows that everything is within range. for ALT the reference range is 9-60 U/L. My question is this, since ive been searching ive seen that different labs have different reference ranges. do they test different? why wouldnt all labs have a standard range that everyone goes by?
What questions should I ask and should I have other tests performed. I recently had a brother die from Liver and Pancritis Cancer and Previously had throat cancer a couple of years ago. Im not sure if it was Thyroid Cancer and they called it throat cancer. Any asstance with this is greatly apprecitated.
In conclusion, we characterized the thyroxine glucuronidation in human liver, intestine, and kidney microsomes and found that UGT1A1 in the liver, UGT1A8 and UGT1A10 in the intestine, and UGT1A7, UGT1A9, and UGT1A10 in the kidney mainly contribute to the activity. The change of activities of these UGTs via inhibition and induction by administered drugs (Kiang et al., 2005) as well as genetic polymorphisms (Miners et al.
The flesh of fish (such as salmon, tuna, and mackerel) and fish liver oils are among the best sources. Small amounts of vitamin D are found in beef liver, cheese, and egg yolks. Otherwise you can take fortified food like cereals etc. Spend time in Sun. Get your liver and parathyroid tested.
Do discuss this with your doctor and get yourself examined. Hope this helps. Please let me know if there is any thing else and do keep me posted. Take care!
Folic acid supplementation in folate-deficient patients with epilepsy changes the pharmacokinetics of phenytoin, usually leading to lower serum phenytoin concentrations and possible seizure breakthrough..."
It however says that initiation of Folic acid and phenytoin together is beneficial.
Since you can't go back and start all over again, you can take a small dose. It has been observed that as los as 1mg dose can perturb phenytoin’s levels, You may take doses lower than 1mg/day.
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