Then, this toxic compound accumulates in the liver
and causes the damage. Furthermore,
alcohol and certain medications such as phenobarbital,
phenytoin (Dilantin), or carbamazepine (Tegretol) (anti-seizure medications) or isoniazid (INH, Nydrazid, Laniazid) - (anti-tuberculosis drug) can significantly increase the damage. They do this by making the cytochrome P-450 system in the liver more active.