, <span style = 'background-color: #dae8f4'>oxymorphone</span>
(Opana), hydrocodone (opioid in Vicodin) and
other less common ones are semi-synthetic, derived in part from thebaine (a small part of
what is in natural opium). The only true synthetics that are common for us with chronic pain are the fentanyl family (Fentanyl, Sufentanil, Alfentanil, etc.) and
methadone, which are come from very different chemical processes. The chemistry is not too complicated, if you have any background in it.