hydromorphone, hydrocodone, oxycodone, oxymorphone
and desomorphine, buprenorphine. Heroin and the other morphines can actually be put in this category as well - as they are derived from natural opiates.
Fully synthetic: fentanyl, pethidine, methadone, and propoxyphene.
There is a huge difference in the terms synthetic and semi-synthetic. But neither has anything to do on if they are produced in a lab. They all are.