I had the option of taking them 3 times a day (every 8 hours) vs
. every 12 hours or switch to the fentanyl
patch. I decided to try the fentanyl
patch since I heard great things about it and I am glad that I did. I was having severe constipation issues that were ridiculous!! I was experiencing severe bloating, cramps, chest pain, and difficulty breathing. I tried fiber supplements, stool softners, miralax, gasx, milk of magnesia and none of them worked.