Oxycodone and liver disease

Common Questions and Answers about Oxycodone and liver disease


It is therefore advisable that opioids should be administered cautiously and may be given at reduced dosages in patients with <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> or: #dae8f4'>disease. If possible an alternative medicine may be prescribed. I hope you find this information useful. Do keep us posted. Good luck!
Hi Linda and welcome to the pain management community. <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span> is safe to take everyday as long as you don't have <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> as it is primarily metabolized by the or: #dae8f4'>liver. I am on the same medication and I have been taking it everyday for almost 2 years. I have been on some form of opioid medication for the past 6 years on a daily basis. It is the acetaminophen (aka tylenol) component that you should be most concerned about.
Yes, I have a chronic <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> or: #dae8f4'>which is Hepatitis C and complications from years of alcohol and drug abuse. The most notable symtoms that I've experienced are chronic fatigue, joint pain, flu-like illnesses, low grade fever for months, and a general feeling of being ill most of the time. You may also develop jaundice(yellow tint) in the white part of your eyes or skin. I developed "or: #dae8f4'>liver" spots on my chest and sore nipples. But everyone is different as they say.
Why would a physician give Lorazapam and <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span> to a patient who has severe <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> damage and also has a history as a youth to drug addiction, and recent serious alcohol addiction that caused the or: #dae8f4'>liver damage in the first place??
Are these items that could be from just taking the <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span> and my body coverts it to this or is the test flawed. my <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span> levels where a little high in my blood but I had just taken my medication one hour prior to the test with grapefruit juice witch I now know not to do cause it can cause high levels but my PM Dr is concerned about the other drugs in my blood.
My husband is one as well, he is on pain management and his <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> is fine I am sure other people will come along and help out, there are many nice people here on this site
One thing I have not see anyone say about the differences in hydrocodone and or: #dae8f4'>oxycodone is that hydrocodone is schedule III while or: #dae8f4'>oxycodone is a scheduled II......
I work in the medical field and I have never seen such an improvement in someone with ESLD (End Stage <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span>). We have seen a specialist at UCSF <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> transplant center who mentioned that their board was going to review disqualifying criteria (cannabis consumption) for or: #dae8f4'>liver transplantation because it has such prevalent presence in California. My partner is not a candidate for or: #dae8f4'>liver transplantation at this time (MELD score @ 12). So all I can say is...
Hello Supportive and Helpful Group! I am on Day 4 already. Between yesterday and today there is no appreciable difference in terms of withdrawal symptoms. I am freezing, fairly tired, in a bit of pain, have sporadic moments of restless arms and legs, and I have that incredibly yucky taste in my mouth and sleep is very elusive. Today I also developed pretty awful stomach pains and diarrhea (yuck) .
I have been on 6-7 <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span> daily for the last four months. Prior to that I was on Norco 10/325 for 18 months. Is it safe for me to quit cold turkey at home? I am in good general health. I have clonodine, clonazepam and neurontin to help me along with Flexeril. Is it safe to stop or do I have to taper? I have been prescribed these drugs for severe, unrelenting pain in both of my feet. I have been to neurologists, rheumatogists, podiatrists, to no avail.
With the controlled release of the med I'm taking now, things seem to be on an even keel compared to the abrupt ups and downs of the shorter acting narcotics like hydrocodone and <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span>. As I've said time and again, all I want is a state of equilibrium in my life where everything seems to be safe and secure....and pain free! I suppose that's a lot to ask for as a human being? Somebody said above that they went fifteen years in hell before discovering a med that offered some relief.
My friend died a little over a year ago, he got so sick and extremely tired went to the doctor and straight to the hospital. He was at end stage <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> from HepC and did not know he had HepC. Toward the end he was continueously hitting the button for the pain killers. He could administer it himself. At that stage all you can do is keep that person comfortable. If your mom has end stage or: #dae8f4'>liver or: #dae8f4'>disease and she positively has no possible way back from damage.
I have seen a Doctor done some test the doctor says that my <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> is enlarged and come back in a year and then we will check its size again. I do not feel that comeing back in a year really has helped me with my symptems nor has it helped me to figure out what is really going on in my body. I am a relitively healthy person, I DO NOT drink nor do drugs and I beleave I eat fearly well, light foods and my weight is average I have good muscle tone cause i do exercise.
or: #dae8f4'>liver injury (hepatitis) secondary to paracetamol is usually seen in people with pre-existing <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> or in alcoholics. It is usually clinically apparent with jaundice and elevated <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> enzymes. Hope that this information helps and hope that you will get better soon. Thank you for using MedHelp's "Ask an Expert" Service, where we feature some of world's renowned medical experts in their fields.
He simply said, take less pills, eat better and your <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> will heal 100%....I did have an ultrasound about 4 months back on the <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> and the results were a fatty or: #dae8f4'>liver. Don't do this, and you will head basically for or: #dae8f4'>liver failure one day.... I found myself thinking one day being 80 years old and really not thinking about the consequences then...such a bad addictive thought to be honest, and really not fair to myself or my family.
Thus, opioids can build up, including their toxic metabolites, with <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> and kidney <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span>. This can cause problems. I've been using opioid analgesics for a long time, also, although not at this level. Opioid tolerance is a large concern, so I rotate my medications -- or: #dae8f4'>oxycodone to morphine to hydromorph to methadone -- every few years. Often I get some benefit in reducing equivalent dose through cross tolerance.
On the other hand, with so little <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> damage, there's really no rush. Generally speaking, this is a very slow moving <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> so he could wait awhile if so inclined. Welcome to the discussion group and feel free to ask questions whenever you want. Please keep us informed.
Long story, but I have degenerative disc <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span>, bulging discs, and arthritis..and I am due to have my baby boy next Tuesday. I have gone through breast reduction surg, epidural steriod shots, chiros, therapy..etc etc. My OB gave me tylox and percs to take for my back during the pregnancy..and also referred me to pain mgmt. My mistake was that I didnt let them know I was pregnant, and was prescribed or: #dae8f4'>oxycodone 30 mg and ms contin 15 mg.
<span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span> and Pregnancy In animal studies on pregnancy and <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span>, the medication did not seem to increase the risk of birth defects or other problems. Limited human studies have also shown that or: #dae8f4'>oxycodone does not appear to cause birth defects. However, as a narcotic, or: #dae8f4'>oxycodone can cause withdrawal symptoms in the infant after deor: #dae8f4'>livery. If you are taking this medication and pregnancy occurs, talk to your healthcare provider. Is or: #dae8f4'>oxycodone Safe During Pregnancy?
I heard that if you drink alcohol while you take Vicodin you have a good chance of getting <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> damage. My question is how long does it take for this to happen and what are the signs if you have it. I'm really scared to ask my doctor about this b/c I abused Vicoden for so many years and drank alot of alcohol with it at times. Sometimes I feel pain down in that area. I really think my or: #dae8f4'>liver is shot from all the years of abuse. I hope not.
It is my understanding that you can have no more that 4000mg/day of tylenol for normal <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> and people with <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> should take as little as needed. I don't think there are studies showing increased damage with normal doseing. there is also a generic or: #dae8f4'>oxycodone that has no tylenol in it.
Hi Jon. Sorry to hear of the pain you have. There are opiates without the tylenol and they are: or: #dae8f4'>oxycodone 5 & 10 mg Oxycontin 10mg and higher (or: #dae8f4'>oxycodone with extended release or 12hr) and there are many others. Talk with your Doc. I believe you can get the Hydrocodone w/o the tylenol, ask your Dr. Like Empathy said, you are not taking a large dose of tylenol but if you are taking the pain medication long term then I would talk with your PCP on getting a pain reliever without the tylenol.
Those with cirrhosis are can also take acetaphetamine but should consult with their doctor for the recommended dosage. I have advanced <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> and I don't know what you mean by hepatic pain. I've never experienced that. The or: #dae8f4'>liver has no nerves. The capsule surrounding the or: #dae8f4'>liver can expand if the or: #dae8f4'>liver enlarges producing intermittent pain at times but those with or: #dae8f4'>liver or: #dae8f4'>disease do not experience pain for the most part.
To this date, this should not be in the blood supply. I'm very suprised. You will experience pain on and off in the <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> area. Sometimes you have more inflammation that other times and this can produce an achy or painful or: #dae8f4'>liver. Sometimes taking too much medication can produce pain too. I'm not sure what can be done about it. Some Doctors are leery of prescribing meds due to the or: #dae8f4'>liver function. Take care and hope you feel better soon.
An overdose of acetaminophen and or: #dae8f4'>oxycodone can be fatal. When a person has an overdose of acetaminophen and <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span> they will have immediate <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> failure and will need a transplant very quickly to stay alive. This is how people commit suicide by taking a bottle of tylenol or tylenol + Oxy. It destroy the or: #dae8f4'>liver within hours. The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness.
If NSAIDs are medically required for the treatment of another medical disorder, a reduced dose should be used for a limited period of time and only by people with stable <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span>. Older women with <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span> <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>disease</span> seem to be particularly susceptible to the hepatotoxicity of NSAIDs and are advised to avoid NSAIDs altogether. Since NSAIDs may cause salt and water retention people with fluid retention problems such as ascites or leg swelling may suffer worsening of these conditions.
If it's just pure or: #dae8f4'>oxycodone, then chances are it's not you, the brand name percocet MIGHT make you feel better than the pure <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>oxycodone</span>, because, as my doctor explained it to me, the APAP acts as a catalyst and it can boost the efficacy of the or: #dae8f4'>oxycodone by almost 50% in some cases. In other words, if you take one percocet (with the tylenol built in) you might need one and a half or even two of the pills without the tylenol in them to get the same result with regard to pain control.
Hoping and praying that the pills did not mess with my <span style = 'background-col<span style = 'background-color: #dae8f4'>or</span>: #dae8f4'>liver</span>. Best of luck ppl. sorry i dont post as much as i should. been busy with family and work. i will make a better effort to keep all the positive energy flowing.
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