Oxycodone and liver disease

Common Questions and Answers about Oxycodone and liver disease

oxycontin

It is therefore advisable that opioids should be administered cautiously and may be given at reduced dosages in patients with liver disease. If possible an alternative medicine may be prescribed. I hope you find this information useful. Do keep us posted. Good luck!
Hi Linda and welcome to the pain management community. Oxycodone is safe to take everyday as long as you don't have liver disease as it is primarily metabolized by the liver. I am on the same medication and I have been taking it everyday for almost 2 years. I have been on some form of opioid medication for the past 6 years on a daily basis. It is the acetaminophen (aka tylenol) component that you should be most concerned about.
Yes, I have a chronic liver disease which is Hepatitis C and complications from years of alcohol and drug abuse. The most notable symtoms that I've experienced are chronic fatigue, joint pain, flu-like illnesses, low grade fever for months, and a general feeling of being ill most of the time. You may also develop jaundice(yellow tint) in the white part of your eyes or skin. I developed "liver" spots on my chest and sore nipples. But everyone is different as they say.
Why would a physician give Lorazapam and Oxycodone to a patient who has severe liver damage and also has a history as a youth to drug addiction, and recent serious alcohol addiction that caused the liver damage in the first place??
My husband is one as well, he is on pain management and his liver is fine I am sure other people will come along and help out, there are many nice people here on this site
I work in the medical field and I have never seen such an improvement in someone with ESLD (End Stage Liver Disease). We have seen a specialist at UCSF liver transplant center who mentioned that their board was going to review disqualifying criteria (cannabis consumption) for liver transplantation because it has such prevalent presence in California. My partner is not a candidate for liver transplantation at this time (MELD score @ 12). So all I can say is...
One thing I have not see anyone say about the differences in hydrocodone and oxycodone is that hydrocodone is schedule III while oxycodone is a scheduled II......
Hello Supportive and Helpful Group! I am on Day 4 already. Between yesterday and today there is no appreciable difference in terms of withdrawal symptoms. I am freezing, fairly tired, in a bit of pain, have sporadic moments of restless arms and legs, and I have that incredibly yucky taste in my mouth and sleep is very elusive. Today I also developed pretty awful stomach pains and diarrhea (yuck) .
I have been on 6-7 oxycodone daily for the last four months. Prior to that I was on Norco 10/325 for 18 months. Is it safe for me to quit cold turkey at home? I am in good general health. I have clonodine, clonazepam and neurontin to help me along with Flexeril. Is it safe to stop or do I have to taper? I have been prescribed these drugs for severe, unrelenting pain in both of my feet. I have been to neurologists, rheumatogists, podiatrists, to no avail.
ACTIC (FENTAYL LOLLIPOPS) AND THEN SWITCHED TO THE FENTAYL PATCHES, I SWITHCED DOCTORS AND WAS TAKEN OFF FENTAYL THEN LOST MY INSURANCE AND PUT ON METHADONE AND OXYCODONE, I AGAIN SWITCHED DOCTORS AND CURRENTLY ON OXYCADONE 30MG 8 A DAY AS WELL AS XANAX WHICH I AM BEING TAPPERED OFF OF NOW, THEN MY OB WANTS TO TAPPER THE OXYCODONE I DON'T WANT TO HURT MY BABY IN NO WAY BUT AT THE SAME TIME I'M WONDERING WHAT KIND OF SEVERE PAIN I WILL BE IN WHEN I AM OFF OF THE PAIN MEDS, BUT I DON'T WANT MY B
With the controlled release of the med I'm taking now, things seem to be on an even keel compared to the abrupt ups and downs of the shorter acting narcotics like hydrocodone and oxycodone. As I've said time and again, all I want is a state of equilibrium in my life where everything seems to be safe and secure....and pain free! I suppose that's a lot to ask for as a human being? Somebody said above that they went fifteen years in hell before discovering a med that offered some relief.
Asking any person who may have knowledge if Oxycodone and the likes can cause Graves disease and bad personality changes? A wife who cares..please help.
My friend died a little over a year ago, he got so sick and extremely tired went to the doctor and straight to the hospital. He was at end stage liver disease from HepC and did not know he had HepC. Toward the end he was continueously hitting the button for the pain killers. He could administer it himself. At that stage all you can do is keep that person comfortable. If your mom has end stage liver disease and she positively has no possible way back from damage.
I have seen a Doctor done some test the doctor says that my liver is enlarged and come back in a year and then we will check its size again. I do not feel that comeing back in a year really has helped me with my symptems nor has it helped me to figure out what is really going on in my body. I am a relitively healthy person, I DO NOT drink nor do drugs and I beleave I eat fearly well, light foods and my weight is average I have good muscle tone cause i do exercise.
Liver injury (hepatitis) secondary to paracetamol is usually seen in people with pre-existing liver disease or in alcoholics. It is usually clinically apparent with jaundice and elevated liver enzymes. Hope that this information helps and hope that you will get better soon. Thank you for using MedHelp's "Ask an Expert" Service, where we feature some of world's renowned medical experts in their fields.
He simply said, take less pills, eat better and your liver will heal 100%....I did have an ultrasound about 4 months back on the liver and the results were a fatty liver. Don't do this, and you will head basically for liver failure one day.... I found myself thinking one day being 80 years old and really not thinking about the consequences then...such a bad addictive thought to be honest, and really not fair to myself or my family.
On the other hand, with so little liver damage, there's really no rush. Generally speaking, this is a very slow moving disease so he could wait awhile if so inclined. Welcome to the discussion group and feel free to ask questions whenever you want. Please keep us informed.
Long story, but I have degenerative disc disease, bulging discs, and arthritis..and I am due to have my baby boy next Tuesday. I have gone through breast reduction surg, epidural steriod shots, chiros, therapy..etc etc. My OB gave me tylox and percs to take for my back during the pregnancy..and also referred me to pain mgmt. My mistake was that I didnt let them know I was pregnant, and was prescribed oxycodone 30 mg and ms contin 15 mg.
Oxycodone and Pregnancy In animal studies on pregnancy and oxycodone, the medication did not seem to increase the risk of birth defects or other problems. Limited human studies have also shown that oxycodone does not appear to cause birth defects. However, as a narcotic, oxycodone can cause withdrawal symptoms in the infant after delivery. If you are taking this medication and pregnancy occurs, talk to your healthcare provider. Is Oxycodone Safe During Pregnancy?
I heard that if you drink alcohol while you take Vicodin you have a good chance of getting liver damage. My question is how long does it take for this to happen and what are the signs if you have it. I'm really scared to ask my doctor about this b/c I abused Vicoden for so many years and drank alot of alcohol with it at times. Sometimes I feel pain down in that area. I really think my liver is shot from all the years of abuse. I hope not.
It is my understanding that you can have no more that 4000mg/day of tylenol for normal liver and people with liver disease should take as little as needed. I don't think there are studies showing increased damage with normal doseing. there is also a generic oxycodone that has no tylenol in it.
Hi Jon. Sorry to hear of the pain you have. There are opiates without the tylenol and they are: Oxycodone 5 & 10 mg Oxycontin 10mg and higher (Oxycodone with extended release or 12hr) and there are many others. Talk with your Doc. I believe you can get the Hydrocodone w/o the Tylenol, ask your Dr. Like Empathy said, you are not taking a large dose of Tylenol but if you are taking the pain medication long term then I would talk with your PCP on getting a pain reliever without the tylenol.
Those with cirrhosis are can also take acetaphetamine but should consult with their doctor for the recommended dosage. I have advanced liver disease and I don't know what you mean by hepatic pain. I've never experienced that. The liver has no nerves. The capsule surrounding the liver can expand if the liver enlarges producing intermittent pain at times but those with liver disease do not experience pain for the most part.
To this date, this should not be in the blood supply. I'm very suprised. You will experience pain on and off in the liver area. Sometimes you have more inflammation that other times and this can produce an achy or painful liver. Sometimes taking too much medication can produce pain too. I'm not sure what can be done about it. Some Doctors are leery of prescribing meds due to the liver function. Take care and hope you feel better soon.
An overdose of acetaminophen and oxycodone can be fatal. When a person has an overdose of acetaminophen and oxycodone they will have immediate liver failure and will need a transplant very quickly to stay alive. This is how people commit suicide by taking a bottle of Tylenol or Tylenol + Oxy. It destroy the liver within hours. The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness.
If NSAIDs are medically required for the treatment of another medical disorder, a reduced dose should be used for a limited period of time and only by people with stable liver disease. Older women with liver disease seem to be particularly susceptible to the hepatotoxicity of NSAIDs and are advised to avoid NSAIDs altogether. Since NSAIDs may cause salt and water retention people with fluid retention problems such as ascites or leg swelling may suffer worsening of these conditions.
coronary, pulmonary or spontaneous bleeding and clotting can occur at any time and hasten death Additionally, it is not uncommon for liver failure patients to wax and wane in terms of their mentation, confusion and overall state. Paradoxically, it's a laxative (lactulose) which can improve their mentation by converting and clearing amonium from the system - which is a function of a healthy liver So it's a roller coaster I'm afraid.
They are small blue 30 mg. Oxycodone is the generic, and the doc has had me on those for over a year now. He writes it for 240 a month which I never take, but I think I can deal with the pain better w/ those than the 40 mg Oxcontin. He wrote a script for 60 40's a couple of weeks ago, and I have ot had it filled yet. Thanks for the info.
So now I'm home I don't take any Tylenol or ibuprofen products and I'm scared to death not knowing what my liver enzymes are right now And how to get them back to normal. I just felt that I didn't get any proper education from the doctors on what to eat what I can't take what I can take and I'm a bit irritated. And I'm terrified. I am still taking oxycodone for pain but I have decided today to wean myself down and I was told that they do not affect any liver enzymes.
Oxycodone (oxycontin) , and as someone else stated, dilaudid are both very good pain medications. I have heard that morphine and methadone are best for long term , although I'm not sure why that is.
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