Its possible side effects include nausea, diarrhea, sedation, polyuria (increased urination), increased thirst, tremors
, hypothyroidism, and weight gain, to name a few. Long-term treatment with lithium or some other mood-stabilizer is usually the standard of care in the treatment of bipolar disorder. There are other mood stabilizers, Valproic acid (Depakote) being the most common. It is not without side effects (e.g.