Nefazodone withdrawal
Common Questions and Answers about Nefazodone withdrawal
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I might have a solution for you after examining the pharmacology of Nefazodone. To get about the same result you had with Nefazodone with no weight gain I would recommend sertraline (Zoloft) combined with Wellbutrin XL. To get a significant antagonizing effect to your 5-HT2 receptors you would need mirtazapine but it is related with weight gain so I would try the Zoloft with Wellbutrin XL which will basically in a SNDRI like Nefazodone and see how it goes.
I've had chronic, severe nausea for the past year and I can't take it anymore. I get nauseated after everything I eat. It doesn't matter what. I can't even have breakfast anymore (I went from eating solids to drinking liquids, and now I can't eat anything at all). Sometimes I feel like I'm not even hungry, and other times I feel horribly hungry. I can only have small meals now and I can't have dairy or bread.
t working as well for me anymore, and I wanted to try to switch my meds anyway to improve my sex life. Well, after a rollercoaster of a year where I tried Wellbutrin first, then Nefazodone, then falling into a very deep depression I realized that I really do need to be on Zoloft. The other pills didn't really help my drive, but they did make sex more pleasurable and had quicker/easier orgasms. Now that I am going back, I am devastated to be losing that part of my life again.
Anyway, there are lots of options - ranging from a number of medications that have been well studied such as nefazodone, mirtazapine, and the tricyclic antidepressants, to supplements that seem to be effective (although probably somewhat less so) such as hypericum and s-adenosyl methionine. Finally there are a number of medications that are not routinely prescribed for depression that might be of use, and that list is a bit long to put here.
In any event, the answer is yes.
(2003, January). Nefazodone decreases anxiety during marijuana withdrawal in humans. Psychopharmacology, 165(2), 157-165.
Haney, M., Ward, A.S., Comer, S.D., Foltin, R.W., & Fischman, M.W. (1999, February). Abstinence symptoms following smoked marijuana in humans. Psychopharmacology, 141(4), 395-404.
Jones, R.T., Benowitz, N.L., & Herning, R.I. (1981, August-September). Clinical relevance of cannabis tolerance and dependence. Journal of Clinical Pharmacology, 8-9 Suppl., 143-152.
The interaction has also been reported in patients receiving atorvastatin, lovastatin, or simvastatin with other potent CYP450 3A4 inhibitors such as azole antifungal agents, macrolide antibiotics, HIV protease inhibitors, and nefazodone. Clinically, high levels of HMG-CoA reductase inhibitory activity in plasma may be associated with an increased risk of musculoskeletal toxicity.
Due to the risk of life-threatening and fatal toxicity, patients with renal or hepatic impairment should not be given colchicine in combination with potent CYP450 3A4 inhibitors such as itraconazole, ketoconazole, voriconazole, nefazodone, delavirdine, protease inhibitors, and ketolide and certain macrolide antibiotics. In patients with normal renal and hepatic function, the dosage of colchicine should be reduced when used with potent CYP450 3A4 inhibitors or within 14 days of using them.
Yes been struggling bigtime. Doc was going to give me my pill of choice.
In my and others experience, the best withdrawal method is a process of cutting back your dosage over time. Going into a rehab unit is pure hell. And anyway you are not an addict. Take it slow friend. In my humble opinion the vicodin you may want to stay on the longest. Percs make me feel depressed. Vicodin does not do that. I am a pain patient. This may sound counter intuitive but oxycontin acts longer with getting a less addictive buzz or high like one does on vikes(hydrocodone).
I have been taking vicodin and tramadol for over 15 years and really want to stop taking them because they are ruining my life. But the pain from withdrawal is unbearable. I am at my wits end n don't know how to ease the withdrawal symptoms. Any ideas?
will i experience withdrawal symptoms? i know that no one can say for sure, but there must be someone out there who can speak to this situation that i am in. i am frightened, or more appropriately, i have a sense of dread about having to go through withdrawal on top of all of the other health problems that i have right now. in may of last year i was diagnosed with multiple sclerosis, and in feb of this year i was diagnosed with crohn's.
I am trying to ween off I am down to 1/2 in morning 1/2 at night. I am feeling withdrawal symptoms already is it going to get worse once I stop? I am taking a lot of vitamin and trying the thomas recipe but I feel terrible and I have to work.
I think the typical withdrawal is 4-5 days of the intense phsyical symptoms. I do not know about methadone. Try wrapping your legs in ace bandage for the rls. It helped me.
Can anyone tell me how long the withdrawal symptoms last when coming off Oxycontin? I've been taking 300mg a day for the last four years because of spinal disease. I've now decided I'd rather suffer the pain than deal with this drug anymore. I no longer have any interest in anything and spend most of my days watching TV. After doing my research, I've decided it's the drug from hell and I really need to stop.
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