Nefazodone serzone
Common Questions and Answers about Nefazodone serzone
serzone
I am 38, I had a complete Major Vegatative Depression in 1997, and was more lor less bedridden for 6 months - Nothing worked for me except SERZONE ( Now Called Nefazodone ) I have been on this Medicine for 11 years - I have struggled with Depression BIGTIME and only ever worked for my Father and my Myself, I could work at my own pace and about 20 hours per week for Dad till 2005, then I quit because I was not relaible due to my Symptoms that have always plagued me, I hate the Morning, I sleep ab
I might have a solution for you after examining the pharmacology of Nefazodone. To get about the same result you had with Nefazodone with no weight gain I would recommend sertraline (Zoloft) combined with Wellbutrin XL. To get a significant antagonizing effect to your 5-HT2 receptors you would need mirtazapine but it is related with weight gain so I would try the Zoloft with Wellbutrin XL which will basically in a SNDRI like Nefazodone and see how it goes.
I've had chronic, severe nausea for the past year and I can't take it anymore. I get nauseated after everything I eat. It doesn't matter what. I can't even have breakfast anymore (I went from eating solids to drinking liquids, and now I can't eat anything at all). Sometimes I feel like I'm not even hungry, and other times I feel horribly hungry. I can only have small meals now and I can't have dairy or bread.
After stopping serzone for anxiety, my husband had a reaction of severe insomnia after trying Lexapro for 3 days. His doctor suggested bipolar and put him on Zyprexa but is weaning him down gradually. He's on 7.5 mg currently. What side effects can we expect if he doesn't really have bipolar (which is our opinion) from this medication? We know the most common ones, but what if he is not truly bipolar? I can't wait for him to get off of it, but he is sleeping soundly again.
There is an anti-d called nefazodone that might be a n option. It's an SNRI class. It's got got known liver side effects but this can be managed through careful monitoring. Brand names are Serzone or Nefadar.
There was a recent study that demonstrated correlation between depression and QT variability. Also for panic disorder.
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Does Serzone cause weight gain and how does it affect your sex drive. This is my first time on this forum and looking for some answers.
Anyway, there are lots of options - ranging from a number of medications that have been well studied such as nefazodone, mirtazapine, and the tricyclic antidepressants, to supplements that seem to be effective (although probably somewhat less so) such as hypericum and s-adenosyl methionine. Finally there are a number of medications that are not routinely prescribed for depression that might be of use, and that list is a bit long to put here.
In any event, the answer is yes.
with no deppression i am now feeling deppressed and i think it is from a melatonine/5-htp combo, i know it is a seratonine uptake drug but i was on Serzone for 17 days and it made me extremely suicidal so could 5-htp be the cause?
I did have this problem many years ago, which is when I was originally given Ambien, and put on an anti-depressant (serzone), which helped. I have been stable without the Serzone for a long time.
I decided to start taking B12, and Magnesium (oxide, crappy absorption) yesterday, and my mood improved somewhat, and some of the obsessive sensations I mentioned earlier have lessened.
I have gone through several days of crying spells, missed work, and hopelessness.
The interaction has also been reported in patients receiving atorvastatin, lovastatin, or simvastatin with other potent CYP450 3A4 inhibitors such as azole antifungal agents, macrolide antibiotics, HIV protease inhibitors, and nefazodone. Clinically, high levels of HMG-CoA reductase inhibitory activity in plasma may be associated with an increased risk of musculoskeletal toxicity.
It started off as only visual symptoms, limited to my left eye. Just before I went on Serzone for depression, they started to get worse. I would see flashes/streaks of light, ghosting, halo's around backlit objects, increased floaters, the odd inability to maintain focus when looking anyone in the eye. And not for nervous reasons. Over the last few years, the previous symptoms have evolved into new ones which follow.
Extreme sensitivity to moderately bright lights.
Hi there,
I just finished reading your comments. Are you taking any prescription
medications of any kind ? Some prescription medications have a light
headed feeling as a side effect. You said you have had phases of depression. During those phases of depression, did your doctor prescribe
antidepressants? Many years ago, one doctor put me on a certain kind of antidepressant. I took that antidepressant for several years. Then for whatever reason that antidepressant stopped working for me.
The only cause I thought later that might have been was I was taking generic serzone (since they took the name brand off the market for liver damage), but I'm not sure if the medicine I tooke was why it happened. It was said to be unusual to have one on my liver by a doctor, but not harmful. It is a collection of blood vessels.
Due to the risk of life-threatening and fatal toxicity, patients with renal or hepatic impairment should not be given colchicine in combination with potent CYP450 3A4 inhibitors such as itraconazole, ketoconazole, voriconazole, nefazodone, delavirdine, protease inhibitors, and ketolide and certain macrolide antibiotics. In patients with normal renal and hepatic function, the dosage of colchicine should be reduced when used with potent CYP450 3A4 inhibitors or within 14 days of using them.
But my understanding from reliable sources is that it is in the same class as Serzone which was pulled off the market due to liver toxicity. Just because Trazadone is still out there I don't believe it is completely safe for everyone. If Serzone is in the same class and pulled off the market, wouldn't you be cautious with the others in the group and drug companies have a tendency at times to withold data.
t working as well for me anymore, and I wanted to try to switch my meds anyway to improve my sex life. Well, after a rollercoaster of a year where I tried Wellbutrin first, then Nefazodone, then falling into a very deep depression I realized that I really do need to be on Zoloft. The other pills didn't really help my drive, but they did make sex more pleasurable and had quicker/easier orgasms. Now that I am going back, I am devastated to be losing that part of my life again.
Yes been struggling bigtime. Doc was going to give me my pill of choice.
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