naloxone and naltrexone

Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. It is marketed in generic form as its hydrochloride salt, naltrexone hydrochloride, and marketed under the trade names Revia and Depade. In some countries including the United States, an extended-release formulation is marketed under the trade name Vivitrol.

It can be confusing to differentiate between Naltrexone, Low Dose Naltrexone and Naloxone. I have been reading other posts in the archives and see this. Naltrexone is FDA approved to treat opiate addiction. The dose is usually 50mg Low Dose Naltrexone is used off label to treat MS, Crohn's Disease, CFS, Lupus, some cancers, and very, very experimentally, Depression. It is not FDA approved for any of these uses, but it is not illegal to use it this way.

Naltrexone is an opiate agonist and should not be taken or admininistered except under the auspices of a physician. It does not help with addictions. It reverses overdoses. It is extremely dangerous to fool with because an addict can inject nalaxone, which will reverse the opiate as long as it is in the system. The addict will fell normal. When it is metabolized the opiate in the system the opiate kicks on and can cause respiratory arrest.

However when she emmigrated here(to NZ) she was transferred onto suboxone. Apparently the naltrexone/naloxone disrupts the absorbtion of alcohol into the bloodstream and she could not ever feel the effects of the alcohol. I have also read of a treatment for alcoholics where they are prescibed daily doses of naltrexone for this reason. To prevent them feeling any "beneficial effects"of alcohol. I hope this helps to answer your question.

OK, I'll try to explain this if I can. We're talking about 3 drugs. Their generic names are naltrexone, naloxone, and buprenorphine (hence called bupe cause I don't wanna spell it out all the time). Now, naltrexone and naloxone are basically the same acting drug. They both can be either used to "reverse" an opiate overdose, or stop an addict from getting an benefit from taking an opiate.

Precipitated withdrawals will come if either Subutex or Suboxone is taken. A common misconception is that the knocking off of the original opiate is done by the Naloxone, but in fact is caused by the Bupe. The Naloxone is only active if taken by an IV route. If taken sublingually as directed, the Naloxone doesn't factor into the equation at all.

I think you may be thinking about naltrexone. Naltexone is a longer acting version of naloxone and is used in the long term care of opiate addicts. It's even implanted under the skin in some people. With naltrexone in your system, the opiate will not give a high (or pain relief). Can you confirm which you're talking about so we can help?

As a patient advocate for medical maintenance for addiction treatment, every single person I know who has taken any dose of Naltrexone/Naloxone has hated it and regretted it. Though I have no idea of it's medical use in HCV treatment, I cannot imagine that the side effects would be any different. I am heard little good said about this medication and urge you to use caution.

you can google the medicine to find out about it =) this is a place to get clean off things and not to tell people what they are and things like that

t fully understand the difference between Naloxone and Naltrexone, but I do know that Naloxone is used like an antidote for opiate overdose and Naltrexone is not. That Suboxone ( naloxone and buprenorphine ) causes eupohria but not naltrexone. Naltrexone isn't addicitve either in low dose or high dose. It produces very different reactions in the body when used in low dose as opposed to high dose.

The proper way to take the subs is to put under your tounge, let dissolve and spit while dissolving to spit out the naloxone in the med??? I was NEVER told to do this? I ask b/c the last few days shes been complainig of aches, pains, cold sweats, etc....which sound like w/d symptoms so im wondering if she's spitting out her meds? 2. He upped her 2 8mg per day and told her that at 6mg she was only maintaining, they needed to find a dose where she would be happy, then taper her from there????

I have to throw my two bits in here- I did the naltrexone thing and it was AWFUL! I mean, it made me feel like total cr*&. I wasn't taking it for cravings but rather it was a combo pill of oxy/naltrexone that was invented in Australia (I took it for pain after I weaned of high dose dialaudid and fentanyl. It was a horrible drug that was the impetus to make me go cold turkey because I felt like my soul was being robbed.

I have to make a rare correction, Eagle-- Suboxone has naloxone, the IV form of naltrexone. I'm sure you have the principals down though-- naloxone is completely irrelevant to the action of Suboxone, and is there for show more than anything-- it does nothing to contribute to the actions of the drug, but is used to deter people from injecting Suboxone, since then the naloxone would be active. Eagle is correct, Cathy-- buprenorphine, Suboxone, and Subutex are all essentially identical.

They affect the mu-opioid receptors in your brain. An ANTAGONIST such as Naloxone and naltrexone literally *antagonizes* (***** with in a very bad way) the opioid receptors, and kicks off any full agonist affecting the mu-receptor, causing extreme dysphoria and pain when given immediately after using opiates. Just remember it *antagonizes.

Temgesic contains buprenorphine as active ingredient. It's a selective opioid agonist. Naltrexone is the opposite, it blocks my1 opioid receptors and TLR4 (which helps to normalize immune function). Why do you think it's addictive? It reduces symptoms that show up after IFN therapy... It's as addictive as aspirin if you ask me...

Suboxone is a medication that contains buprenorphine and Naloxone. The naloxone is added to the buprenorphine to lessen the odds that a user will abuse the medication. Because Naloxone can sometimes cause symptoms of opiate withdrawal, pregnant women wanting to take buprenorphine are normally advised to take Subutex instead. Subutex is exactly the same as Suboxone, but it contains no Naloxone, only buprenorphine.

C then taking 50mg tablet of Naltrexone, had been using for at least 12 months? just wonder what others expierienced, and oh yea it was quick but.......

I need help badly and quickly. I have been on anywhere from 100 to 150 mg of Methadone for 4 years. I am seeing a new doctor now and he is not very kind. Basically I blame the methadone for my divorce from the father of my daughter and the love of my life, bankruptcy, and the loss of a fiancee. I hate being on this drug b/c I remember how good I used to feel before I started taking it. I wouldn't get tired as much, etc...

Suboxone is the brand name for a medication consisting of buprenorphine and naloxone. Buprenorphine is a thebaine derivative with powerful analgesia approximately 20-40x more potent than morphine. Buprenorphine is a partial agonist and antagonist of the opioid receptors in the central nervous system which means when the its molecule binds to a receptor, it will transduce only a partial response in contrast to a full agonist such as morphine.

JoAnna, I can't help you find a doctor, but I can explain the Suboxone/Subutex question you asked. The naloxone in Suboxone is placed there only to discourage people from using it via the IV route. When you let a Suboxone tablet dissolve in your mouth, you're getting a dose of Bupe and a dose of naloxone. The Bupe is absorbed into your system but the naloxone is not.

Naltrexone is not Temgesic, I know Temgesic from the 1980 s and would not be going near it again. Naltrexone is licensed for withdrawal from opioids and alcohol. It comes in 50 mg tablets and up to 300 mg can be prescribed in acute stages of withdrawal. Naltrexone is an opiod antagonist and is not know to have addictive properties or be a an analgesic of any sort.It does not get you high. At a low dose it appears to regulate the immune system though no clinical trials have been done.

Rapid drug detox is a process of blocking the opioid receptors with specific medications called Naloxone and Naltrexone which cause you to have immediate withdrawal from the narcotics in your system. This is done while you are under anesthesia, so that most of discomfort is past when you wake up. You are given a variety of medication to handle the rest of the symptoms and are usually in pretty good shape in a few days.

I wanted to ask...has anyone tries an opiate blocked? Does itwork if so and was the blocked hard to get off?

For the sake of clarification in this thread, it is important to understand that naltrexone and naloxone ARE similar drugs (one lasting longer). But that suboxone (buprenorphine AND naloxone) is NOT the same as naltrexone. Madge, since you are withdrawing this time on your own w/o the aid of britlofex and naltrexone, what are your plans this time around? Are you not able to return to the outpatient clinic or do you not want to?

Naloxone and naltrexone

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