Mycophenolate for ms

Common Questions and Answers about Mycophenolate for ms

cellcept

778275 tn?1326913623 I can sort of answer your first question. Mycophenolate mofetil (MMF) or Cellcept has been extensively researched for its use in myasthenia gravis. Also, it carries a FDA black box warning that it may increase your chances of infection, lymphoma and congenital malformations (for pregnant women). Also, its optimal dose is yet undecided. Pyridostigmine (Mestinon) is the usual first line treatment for MG.
Avatar m tn I am now on valacyclovir for prophylaxis and supression, because I must continue mycophenolate use. Of course, there is no point in doing this if I do not have a latent HSV-1 or HSV-2 infection. On the other hand, I am reluctant to allow a recurrent opportunistic infection. Moreover, I have a regular but intermittent partner who I have informed about these developments.
4848471 tn?1372238752 I signed up for Tecfidera before I learned there was a PML risk for that drug as well. I really need some guidance here!
645800 tn?1466860955 He then pointed out 12 lesions in the MRI for me stating that they were not classic MS, but also not non-significant either and could be MS,. He then added that my LP wasn't indicative of MS, but that didn't mean I didn't have MS. This was a major leap for him as previously he had been saying that my problems were all from a narrowing of my spinal cord near the base of my brain.
Avatar m tn however, there is no documented increased cancer risk specifically with the use of long-term mycophenolate use. the less immunosuppression one takes over time, the better however.
Avatar f tn And immune suppresant mycophenolate for 6 months. I am grateful for your thoughts. Apologies in delay replying I have been unwell.
Avatar m tn My doc is trying to reduce the dose. Since I was on tacrolimus only(as Mycophenolate causes TLC to go down in two occasion), sirolimus 1mg is started along with reduced tacrolimus(2mg BD, Tac level ~4.5). But the creatinine is still high(1.8). It seems some side effect of Sirolimus is also coming as the TLC is 3400 and platelet is 80,000. What do you suggest to bring creatinine under control? What is the way to determine the exact required dose of tacrolimus?
422425 tn?1307992990 Billydude and cudagirl: I did some research, and "grade" does play into diagnostics of T-cells and auto-immune related conditions. It appears from what I read to be used most often with cancers and HIV but can be used with any auto-immune condition. What I could not find was a chart of what was a bad or good level. Without that kind of comparison, it's like not knowing anything at all. Billydude: You said that you take Cellcept/Mycophenolate for Sjogren’s?
Avatar m tn I have been having electrical shocks in my left calf now for about a year and a half. After this diagnosis I was told to continue with my Gabapentin {3x a day @300mg} but I was also told that a possible Botox shot in the surface area of my left calf might also end this pain. Can anyone tell me what possible effects the Botox shot might have on me such as adverse reactions etc.
1054753 tn?1339968724 i do not think that the loose bowel movements are directly related to the transplant itself. they could be from the medications such as mycophenolate or ursodiol. sometimes certain infections can also contribute. If the liver tests are OK, then the loose bowel movements are not from the liver.
Avatar m tn additional agents such as mycophenolate (cellcept) may be necessary or in cases of severe rejection a medication such as thymoglobulin may be needed.
Avatar f tn Hi all My wife has SLE which about 8 months ago began to come undercontrol with mycophenolate.
Avatar f tn There is another drug, called Cellcept (mycophenolate and another one related to it), that are being used off-label for some MS patients. I think SharleneMA was prescribed it. Historically it has been sued for severe autoimmune diseases like RA and Lupus. It is also a potent immune-suppressive chemo-type agent that carries the usual risks. However, it is developing its own history of PML and now carries a Black Box Warning for PML.
Avatar f tn I have been taking predisone and mycophenolate for the past 9 yrs and until the biopsy I thought everything was status quo. Again thank you for all the information.
Avatar f tn I have auto imune hep I have had it for 5 years I keep really good health and work full time I am on Azathiropine 50mg in the morning and 25 at night.
Avatar f tn I know testing for MS is an exclusionary game. But with regard to the MRI, what is the best and most accurate way to go? Open? Closed? With contrast? Thanks!
Avatar n tn Also, I have IgA nephropathy and have been on low dose immunosuppressant (mycophenolate mofetil 250 mg twice daily) for the past 1.5 years. 4 days ago, I noticed a little bump in on my labia minora. and I thought maybe it was a boil and tried to break it. It is now pus filled and looks like a zit. its just the one. I have no tingling or itching tho there is some pain now after i messed abt with it which is kinda like the pain i feel with zits anywhere.
Avatar n tn Track down another neurologist in your area, one who specializes in MS. She needs a great deal of testing. For lots of helpful information, click on our Health Pages, at upper right of screen. The best of luck to you both.
Avatar f tn The only way they can figure out you have benign MS is after a lifetime of MS. I have had MS for 47 years and mine is mild in comparison to most people I know with MS. My brain MRIs seldom change and I had a big attack at age two and gradual changes starting in my forties. The only reason I am not a DMD is I have cancer and can't take one. I know my MS could accelerate at any time or not. If I were new to MS I would at least be on Copaxone.
434698 tn?1207281597 Hi there Stormy, Welcome to the mystery and confusion of Multiple Sclerosis! I have only just joined this site and I have not been diagnosed yet but have been waiting for a diagnosis now for 3 years, or for someone to tell me that it ISN'T MS! Your symptoms sound typical of MS but I am not a Dr and without an MRI and a specialist to do the necessary work up, you will not get a diagnosis, so we would only be making a very large guess.
Avatar m tn I have had MS for 48 years. I worked construction and Veterinary Medicine for many years with MS. I drove service vans and lifted heavy things and climbed ladders. I lifted dogs for 12 hours a day working at Vets. It was a combination of MS and Cancer that finally put me out of commission. I still ride horses and hike and train dogs. Life with MS is a challenge but not as bad as I thought it would be. It took me two years to be diagnosed even though they saw MS on the first MRI.
Avatar f tn I went to neurologists for 40 years and it finally took an MS Specialist to diagnose MS. I did have lesions on my MRI and an abnormal lumbar puncture to diagnose MS, but not everyone has both.
640347 tn?1228533326 I just wanted to point out, in case you hadn't noticed in the health pages, that lumbar spine MRI's aren't done for MS because the lumbar area is outside of the central nervous system. It would make sense to have cervical and thoracic spine MRI's, especially if you have symptoms that could come from those areas. Did your neuro look at the MRI images? Sometimes the radiologists make mistakes.
Avatar f tn Contact the NMSS and contact your local chapter and ask for references for local neuros who have MS experience. Here is the link http://www.nationalmssociety.org/find-a-chapter/index.aspx Finding a caring neuro makes a huge difference. I changed doctors too when the MS dx came about, just did not click with the first neuro and knew he was not the right doctor for me.
Avatar f tn You present a great deal of information. To me much of does not go together. Forinstance spinal taps do not show lesions. Also MS lesions do not exist outside of the central nervous system, like by your ears. As others have urged, you need to have a very plain speakig conversation with your neurologist. If he or she is mentioning spinal tap lesions and MS lesions near your ear I would urge you to find a new neurologist, quickly.