Your demyelinating disease could be due to
multiple sclerosis (most common), optic neuritis, devic’s disease and encephalomyelitis. However, persistent headache is more common with encephalomyelitis, which is inflammation of the brain and spinal cord due to post infection/injury. Other symptoms could be delirium, seizures and coma. But in multiple sclerosis symptoms could be loss of muscle coordination & strength, normal sensation and vision.