Multiple sclerosis treatment monoclonal antibodies

Common Questions and Answers about Multiple sclerosis treatment monoclonal antibodies

multiple-sclerosis

Avatar n tn It resembles multiple myeloma and similar diseases, but the levels of antibody are lower, the number of plasma cells (white blood cells that secrete antibodies) in the bone marrow is lower, it has no symptoms or problems, and no treatment is indicated. However, multiple myeloma develops at the rate of about 1-2% a year, so doctors recommend monitoring it yearly. In rare cases, it may also be related with a slowly progressive symmetric distal sensorimotor neuropathy.
382218 tn?1341181487 MS Damage May Be Reversed By Leukemia Drug -------------------------------------------------------------------------------- Researchers in the UK found that alemtuzumab, a drug initially developed to treat leukemia, stopped the advance of multiple sclerosis (MS) in patients with early stage active relapsing-remitting multiple sclerosis (RRMS) and may even have reversed some of the damage caused by this debilitating neurological disease.
Avatar f tn If you’ve received monoclonal antibodies, you must wait 90 days after recovering from COVID-19 to receive the vaccine. According to the Food and Drug Administration (FDA), monoclonal antibodies are proteins made in a laboratory that mimic your body’s immune response. Dr. Englund says some people might not need to be hospitalized for COVID-19, but might receive these antibodies from their doctor as an infusion treatment to help fight the virus.
1831849 tn?1383228392 I have a very mixed reaction to this news - withholding this drug directly affects many people, including a few I know personally, who see this as a 2nd or 3rd line treatment, having failed on others. I have been on record as to how Campath/Lemtrada has been groomed to create huge profits for Genzyme/Sanofi. In this case I do wish the FDA had approved Lemtrada, and left the final INFORMED decision up to the person with MS and their medical team.
12832842 tn?1448728801 //newsroom.ucla.edu/releases/preliminary-clinical-trial-shows-great-promise-for-new-multiple-sclerosis-treatment I'd rather characterise the doctor as "had a hypothesis and secured funding" rather than "believed in it so much and raised money". Semantics, perhaps, but the first is what scientists often do. The latter sounds too much like the lone-wolf maverick doctor narrative, and that rarely ends with anything of use.
645800 tn?1466860955 Late on Friday, May 27, 2016, the United States Food and Drug Administration announced the approval of Zinbryta™ (daclizumab) for adults with relapsing forms of multiple sclerosis (RMS). This monoclonal antibody is self-administered subcutaneously (under-the-skin) once per month and has been shown to reduce the number of relapses as well as new or newly enhancing lesions, as compared to another approved MS medication and to placebo, in two separate studies.
739070 tn?1338603402 Conclusions Positive status with respect to anti–JC virus antibodies, prior use of immunosuppressants, and increased duration of natalizumab treatment, alone or in combination, were associated with distinct levels of PML risk in natalizumab-treated patients with multiple sclerosis. (Funded by Biogen Idec and Elan Pharmaceuticals.) http://www.nejm.org/doi/full/10.1056/NEJMoa1107829?
Avatar m tn http://hbvadvocat.blogspot.ca/2013/12/experimental-treatment-would-help.html?
Avatar f tn There is no well-established treatment. Treatment with interferon, corticosteroids, or cyclophosphamide (cytoxan) has not shown any consistent results although some patients appear to respond to one or a combination of these drugs (5).
Avatar m tn It is really a shock to get this diagnosis and then you worry when the symptoms are not getting better with treatment. But, please be patient with the treatment as it will eventually work and her symptoms will calm down. Is she still in the hospital? The disease is not curable but it can be slowed down as Deb has already explained.
Avatar m tn my sister (24) was diagnosed Multiple Sclerosis in 2010, responded to steroid. now she suffered sudden & complete loss of vision in her left eye. she has been put on SOLUMEDROL. please suggest any available treatment modalities world over ? chances of return of vision ??
Avatar m tn i had been diagonised with multiple sclerosis in the year 2001. now i am not able to walk. i am also not able to see clearly. my speech is also not clear. i think my type of ms is primary progressive since my condition has worsened gradually. pl suggest some medicines or other alternative therapy.
Avatar f tn The two most common causes of monoclonal protein in serum or urine are multiple myeloma or monoclonal gammopathy of undetermined significance (MGUS). The diagnostic triad for multiple myeloma includes significant paraprotein in the serum or urine, more than 10% to 15% plasma cells in bone marrow, and the presence of bony lesions. MGUS, on the other hand, is characterized by a serum IgG monoclonal protein with no or only a small amount of protein in urine (Bence Jones protein < 1 g/24 hr).
924530 tn?1263979683 i have heard there will soon be new treatment available using antibodies and should be less deblilitating than interferon/+peg? Does anyone have any news about this treatment?
692738 tn?1235762887 There is no well-established treatment. Treatment with interferon, corticosteroids, or cyclophosphamide (cytoxan) has not shown any consistent results although some patients appear to respond to one or a combination of these drugs (5). Reported Report this Spam Abuse by hippygem Leave a Note Send Message Add as Friend hippygem Female, 48 years Australia Member since Mar 2006 Mood: hippygem is tired as usual Journal Entry: "Written by LINDA MCINNES (AHCS) Editor/A...
1139187 tn?1355706647 This test helps to characterize the type of abnormal protein that is present and further studies may be necessary to determine the amount of abnormal protein that is present. The abnormal protein is referred to as monoclonal gammopathy or monoclonal paraproteinemia. The term monoclonal refers to the presence of these proteins as being derived from a single clone of abnormal cells, more suggestive of a malignant process.
Avatar f tn What you haven't said is how old your mother is, whether she has other health problems that make covid worse, etc. Know that the vast majority of those who get covid do survive. If you live in an area where doctors are up to speed on current treatments and have them available, there are some pretty good mitigating treatments (mostly steroids) and one almost cure if it's given early enough, which are monoclonal antibodies.
335728 tn?1331414412 Martin, MDApril 15, 2010 (Toronto) -- Nearly 71% of people with early relapsing-remitting multiple sclerosis (MS) treated with the experimental MS drug alemtuzumab showed no evidence of disease activity four years into a study, researchers report. That's twice the percentage of patients treated with the approved treatment, Rebif, says researcher Alasdair Coles, PhD, of the University of Cambridge.