Multiple sclerosis genetic studies

Common Questions and Answers about Multiple sclerosis genetic studies

multiple-sclerosis

A Genetic Cause For Multiple Sclerosis Is Identified And Funded By Science Patron, Jeffrey Epstein The CYP27B1 gene is discovered by Oxford University to be a leading cause for multiple sclerosis NEW YORK, June 15, 2012 /PRNewswire/ -- A recent study at Oxford University in England and published in Annals of Neurology, has identified a gene that causes vitamin D deficiency and may also be the cause of multiple sclerosis.

Recent studies In 2005, researchers at the Serono Genetics Institute (SGI) achieved a major milestone in identifying and creating a register of genes involved in Multiple Sclerosis (MS). For the first time in this disease area, researchers identified 80 genes involved in the inflammatory and neuro-degenerative pathways of MS, based on a 40% genome scan comparing the genetic profile of a total of 1,800 people with MS and healthy individuals in different populations.

6% had relapsing remitting multiple sclerosis, 9.4% primary progressive multiple sclerosis and 6% clinically isolated syndrome. Nearly 40% of our multiple sclerosis patients with disease duration >10 years (mean = 16.2 ± 5.3 years) remained with no or mild disability (Expanded Disability Status Scale [EDSS] 3). Also, about 30% of patients with relapsing remitting multiple sclerosis showed benign disease evolution (EDSS 3) more than 20 years (mean = 24.0 ± 3.3) after onset.

Demyelination is due to a loss of myelin from the nervous system. The most well known demyelinating disease is Multiple Sclerosis. Demyelination has no popular known cure, though work is going on in the fields of genetic engineering, tissue culture, stem cell therapy. Everyone working in these fields hopes to see a result soon, due to the debilitating nature of these diseases.

I just read in an answer to a post about Multiple Sclerosis that a person with migraines for a long time is expected to have some tiny brain lesions with age (40+). Should I worry about my numbness? Is this a "normal" consequence of my long-term migraines? Should I do a MRI? I'm a bit scared about this, Any suggestion very much appreciated!!

The most common genetic disease causing pituitary tumors is called MEN-1 (Multiple endocrine neoplasia) where glands other than the pituitary, like parathyroid, pancreas also may be involved. This is inherited in an autosomal dominant way. So, if it runs inyour mother's family, you would have inherited it from your mother, and she too would have this disease. Recent studies indicate that some forms of pituitary adenomas also have a genetic component.

I found this site the other day and it also has good articles on MS research. file:///Users/Charley/Desktop/Multiple%20Sclerosis%20Resource%20Centre.

↓ Full text MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.↓ Full text MitoQ, a mitochondria-targeted antioxidant, delays disease progression and alleviates pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis.

Vitamin B12 deficiency is associated with peripheral neuropathy, which causes tingling, and numbness, overlapping symptoms of multiple sclerosis. Multiple sclerosis is a chronic demyelinating neurological disorder where the disease phase is characterized by active phase and remissions. It has multiple symptoms and signs and is a diagnosis of exclusion.

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