multiple sclerosis diagnosis brain lesions

do you have to have active lesions in the brain on MRI in order to have M.S. My husband was diagnosed with M.S. and is driving himself crazy denying it. He had an MRI of the brain that showed multiple foci of T2 and FLAIR hyperintensity in the white matter of both cerebral hemispheres including approximately 5 small lesions in the periventricular white matter, lovated at the callosal sptal margin and oriented perpendicular long axis of the lateral ventricles.

d also like to know if a head CAT scan could also detect lesions in the white matter typical to multiple sclerosis, even if that CAT scan was initially made to rule out possible brain trauma due to a head blow. So basically, is it possible for a neurologist to suspect from multiple sclerosis by looking at a regular CAT scan, or only through MRI? Sorry to bother, I'd really appreciate a reply since the ghost of multiple sclerosis is driving me insane.

has anyone had a diagnosis of ms with brain lesions but negitive ep studies and nagitive spinal tap?

, gliosis) of the brain that will show up as T2 hyperintensity. Multiple sclerosis (MS), as you know, is an inflammatory demyelinating disease that affects the central nervous system. To make the diagnosis there are specific criteria, in which objective neurologic findings are present affecting 2 or more locations in the nervous system in 2 or more episodes. In order to make this diagnosis, a detailed history and neurologic examination are required.

It has multiple symptoms and signs and is a diagnosis of exclusion. The symptoms of multiple sclerosis are loss of balance, muscle spasms, numbness in any area, problems with walking and coordination, tremors in one or more arms and legs.

Lesions have orientation and configuration compatible with the clinical diagnosis of multiple sclerosis. I have an appointment with the neurologist next week, but would like to have an idea of how indicative this impression might be to lead to a diagnosis of MS. Any replies would be appreciated.

Most of your symptoms are related to Multiple sclerosis. Multiple sclerosis causes muscle weakness and nerve damage all over the body. Hoarseness may be caused by neck muscle weakness and paralysis of the vocal fold as a result of multiple sclerosis. Hoarseness may or may not be related to the other symptoms. One of the other causes of hoarseness of voice and severe pain in the back is Aortic dissection. It is a serious condition.

I was diagnosed with multiple brain lesions (none enhanced), a negative LP, and clear C-spine and T-spine MRIs. The neurologic exam did reveal I have spinal cord lesions, they're just invisible on MRI. My neuro exam is pretty markedly abnormal. Check out the other Health Pages, too. There's all kinds of info there. Cheers!

I don't think so. My experience with MRIs and lesions is based on my own brain as well as work I've done in the field (but I'm not a physician). MS lesions are typically quite visible, looking like white spots or splotches, often with poorly defined edges. Use your favorite search engine to see sample images, and you'll note the difference between those and the MRI you posted. Anyone who wants to correct my impression of this MRI and MS lesions, please do so.

You may be under evaluation for Multiple sclerosis. Multiple sclerosis is a disease that primarily affects the central nervous system (brain, spinal cord, nerves from the eye, the optic nerves). Symptoms may be mild to severe, ranging from tingling and numbness to paralysis. There is not one test alone or one symptom that can diagnose MS, but there are well-established criteria that help neurologists make the diagnosis.

Hi I am 48 years old. I am a survivor of Breast Cancer for about 2 years now. For the past year and a half I have been experincing numbness in left side of my face, eye. I have had tremoring in the face, and hands. The pain in my feet and legs is unbearable at times. I have trouble keeping my balance as well.

The various causes of brain lesions on an MRI are brain aneurysm, brain arteriovenous malformation, brain tumor, hydrocephalus, stroke, multiple sclerosis and traumatic brain injury. A strong degree of suspicion needs to be kept for multiple sclerosis. . Multiple sclerosis is a chronic demyelinating neurological disorder where the disease phase is characterized by active phase and remissions. It has multiple symptoms and signs and is a diagnosis of exclusion.

http://www.medhelp.org/forums/Multiple-Sclerosis/show/41 Specifically, this Health Page describes the lesions found in MS: http://www.medhelp.org/health_pages/Multiple-Sclerosis/How-MRIs-Show-Lesions-in-MS/show/23?cid=36 Also, what a typical MS work up entails: http://www.medhelp.org/health_pages/Multiple-Sclerosis/Common-Blood-Test-Youll-See-During-the-Diagnosis-Process/show/446?cid=36 Good luck and keep us posted.

//www.medhelp.org/health_pages/Multiple-Sclerosis/Lesions-vs-Symptoms/show/61?cid=36 and http://www.medhelp.org/health_pages/Multiple-Sclerosis/Spinal-Cord-Lesions/show/764?cid=36 and http://www.medhelp.org/health_pages/Multiple-Sclerosis/How-Can-a-Person-with-MS-Have-a-Negative-MRI/show/161?cid=36 You will likely have many more questions. That's one reason we are here! Welcome.

It is important to make note that white matter lesions on a brain mri does not necessarily mean Multiple sclerosis. White matter lesions can be seen in various conditions. These represent micro vascular ischemic changes in the brain hence these white matter abnormalities on mri are common in patients who have microvascular and macro vascular risk factors like history of hypertension, diabetes and high cholesterol.

or any of the other buzzwords they are currently using to deny to older patients that their MRI brain lesions are, indeed, MS lesions. Spinal MRI lesions cannot be age-related! Regarding your brain MRIs, don't forget to have them checked for brain atrophy. My initial radiologist never mentioned any brain atrophy on my brain MRI: It took a radiologist at Mayo Clinic (reading the same film for an ALS inquiry) to point out the atrophy.

There are a few scattered focal areas of increased sginal within the periventricular white matter which are nonspecific but would support the diagnosis of multiple sclerosis. However, there was no contrast enhancement. No evidence of a mass. The remainder of the study was within normal limits. And just a week ago, MRI was repeated on the cervical and thoracic spine, and I was told there were no changes from the previous studies, but I do not have the written reports yet. There you have it.

21800/abstract Abstract Objective CD4 T-cell–dependent macrophage activation directed against a myelin or oligodendrocyte antigen is generally thought to be the mechanism causing myelin destructio...n in multiple sclerosis (MS). However, areas within expanding MS lesions may exhibit prominent oligodendrocyte loss and apoptosis in the absence of infiltrating lymphocytes.

m new to this forum and just had a couple of questions regarding possible MS diagnosis. In July of 09 I had a MRI of my brain which showed a left frontal lesion measuring 1.4 x 1.2 x 1.4 cm. I had another in August 09 which measured the lesion at 1.0 x o.6 x 1.2 cm. I also had a third one in August 09 which showed another decrease in size. (sorry don't have those results in hand). My neurologist impression is ( Solitary focus of demyelination left frontal brain unclear etiology).

6mm in left frontal parietal says consistent with clinical diagnosis of multiple sclerosis can not see ms nero till june 25 do you think this is enough to get a diagnosis have had all test to rule out everything else thanks so much for any answer

that developed in patients with relapsing-remitting multiple sclerosis. Black holes are lesions MS can cause in the brain, and these lesions, if permanent, represent areas where the most severe and irreversible brain tissue damage has occurred.

Because the clinical radiologic diagnosis of multiple sclerosis is still challenging as a result of the nonspecific appearance of multiple sclerosis plaques on T2-weighted imaging, the prominent perivenular spaces may be a sign we can identify on conventional MR imaging to increase our clinical suspicion for multiple sclerosis.

He there, I am new to this site. I was wondering how you made out with a diagnosis. I had my mri and results showed I had lesions in the juxtacortical position and was told I didn't have MS. Even though I am experiencing the symptoms and the fact that My mom has MS. How are things with you?

It is important to make note that white matter lesions on a brain mri does not necessarily mean Multiple sclerosis. White matter lesions can be seen in various conditions. These represent micro vascular ischemic changes in the brain hence these white matter abnormalities on mri are common in patients who have microvascular and macro vascular risk factors like history of hypertension, diabetes and high cholesterol.

I'm just wondering how much brain atrophy play in the diagnosis of the type of MS you have. When I first started having symptoms I went into the ER and they did a CT. The neurologist came and said that my brain was too small for someone my age and then went on to ask if I was in special ed/graduated hs. She said it was brain atrophy and that it was probably congenial.

Multiple sclerosis diagnosis brain lesions

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