Your demyelinating disease could be due to
multiple sclerosis (most common), optic neuritis, devic’s disease and encephalomyelitis. These include metabolism errors, exogenous toxins released by virus, autoimmune disease, leukodystrophy, demyelination, and radiation effects. Spasticity, muscle weakness, paralysis, hyper-reflexia and movement disorder may be the clinical features associated with white matter disease that need to be evaluated thoroughly.