Don't have that problem with the biggest reasons I waited as long as I did on a 24 hour pain control. Morphine
just don't work for me, so the patch was replaced with the morphine
timethe patches! I can tell if I forgot to replace the patch and let it go a day later, I am hurting something fierce. For me, the patch is easier for me to "keep track" of my pain and when it's time to talk to the doctor about changing dosages or break through pain medication.