Morphine onset of action

Common Questions and Answers about Morphine onset of action

avinza

Avatar m tn A partial µ-opioid receptor agonist, its mixed agonist/antagonist activity affords it a lower risk of dependence and abuse than full µ agonists like morphine. Meptazinol exhibits not only a short onset of action, but also a shorter duration of action relative to other opioids such as morphine, pentazocine, or buprenorphine.
Avatar m tn I am now on 10 mg of morphine, basically as many times a day as I need it. That is the type of person I am I guess: I just have to know that it is there if I need it in order to stop. It was the same when I quit smoking 20+ years ago...as long as I had access to cigarettes I could do it: without any I would panic...So I am taking about 20-30 mg of morphine per day..which is a big drop from 500/day...and I feel fine...next week I will drop to about 10 mg/day...and then nothing after that.
Avatar f tn Naloxone is a μ-opioid receptor competitive antagonist, and its rapid blockade of those receptors often produces rapid onset of withdrawal symptoms. Naloxone also has an antagonist action, though with a lower affinity, at κ- and δ-opioid receptors.
981443 tn?1250115802 Both as the result of this and the pharmacokinetics of oxymorphone, the IR tablets have a de facto duration of action of 5 to 13 hours (the mean would seem to be around 7 hours with a moderately small standard deviation amd a left-skewed and leptokurtic frequency distribution) in patients with normal kidney and liver function.
Avatar m tn m interested in hearing from anybody who has had similar symptoms, or a similar course of action before getting a diagnosis. I have never really heard of tinnitis or vertigo being symptoms of MS, and those are the main reasons I even started pursuing medical help to begin with. The doctors have ruled out some explanations (like the acoustic neuroma), but there are still other possibilities on the table (Meniere's disease, or even high blood pressure for example).
Avatar n tn It kind of sounds like a form of Action tremors, but I have to agree with mkh9.
Avatar n tn I am tapering off morphin and have gotten to a point where I really just want to stop the taper but I am scared of how bad the wd may be? I have gone from 60mg of time release morphine down to 30mg. I have been doing this 3 months now and am really wanting to stop it all together. I did stop vics ct 3 months ago also and that was a tough ct wd. Any advise or simalar stories would be greatly appreciated!! HELP!
766574 tn?1238465473 hello.i don't know if there is someone out there with almost the same issues that i have.i take 2 kinds of morphine,depression pills,humira shots,i'm just a walking pharmacy.how do you deal with your pain, cause i'm tired of it.?
Avatar m tn Hi HopesNeverLost. Yes I absolutely need the morphine although I do try hard to only take what I need. If I didn't have it I wouldn't probably be around but I also do not want to get rely on it more and more either. My apologizes to everyone I was in multiple mva's (3)in the span of 10 months which weren't my fault. Only way I type on here is laying down on my back which also is not what or how one wants to.
Avatar m tn The onset of action ranges from 45 minutes - 1 ½ hours, and the duration of action is six hours. Diazepam carries a bi-phasic half-life of 20-50 hours (for Diazepam), and 30-200 hours (for Desmethyldiazepam). Valium is indicated for the long-term management of generalized anxiety and tension-anxiety. Tolerance will not develop to the anxiolytic property of Diazepam, although tolerance will develop to the sedative/hypnotic property.
Avatar m tn The long term effects of Morphine sulfate on the overall health of the human body. Including heart health, gastro-intestinally, and other organs. I know someone who has been taking it for at least at least 10+years. I am getting worried about this person. A few years ago he had a very bad stomach problem, and they could never figure it out. I pretty much thought it had something to do with the morphine. Any advice? He needs it for his back.
Avatar f tn Second - is this a short acting (SA) or is it a long acting (LA) Morphine? 60mgs of Morphine is one heck of a one time dose. I would not take it. There could be serious complications, especially if you your system is opiate naive. Don't take it.
Avatar f tn What is the onset of action after taking a dose of the immunoglobulin.
Avatar f tn The mechanism of action is hepetic (liver) where in aproximately 15% per MG of codeine is converted to morphine. I believe the max amount of codeine the average liver can process is around 300-400mg of codeine which MEANS at the very worst you are on the equivilant of 60mg morphine. IMO this wont be a hard one to get off...and BTW...You should get off them before it does become a problem!
Avatar n tn [10] It reduces the amount of codeine converted by CYP3A4 into norcodeine thus increasing the amount metabolized into morphine. Morphine itself, however, is not affected by grapefruit juice, as it is not metabolized by the cytochrome P450 system. * Cyclosporine (Neoral). Blood levels of cyclosporine are increased if taken with grapefruit juice. A plausible mechanism involves the combined inhibition of enteric CYP3A4 and P-glycoprotein, which potentially leads to serious adverse events (e.g.
Avatar n tn Get a diagnosis from your doctor after scans are done, and then you can decide your course of action. Specialized Physical Therapy, not the standard stuff, healed my back after two years on the most intense pain I've ever had, and using morphine 24/7.
Avatar n tn http://www.northcoastmed.com/insulin.
Avatar f tn Anyways, Onc/surgeon is recommending epidural for pain management ( I control the drip, just as with Morphine, etc. drips) instead of the traditional pain med stuff. The cath will be in place before surgery so when I wake up in recovery, it is already in action. I love the idea, just wondering if anyone out there has had this experience post surgically?
Avatar f tn After he/she takes the x-ray, they will go over them to determine what plan of action to take. After a few treatments, you should start to feel better.
Avatar f tn Have a lump to the back of my groin, upper of my thigh, think it a cyst, it the size of a pea. Suffering with knee aches and pains at the moment too also getting constipation. Get the odd lower stomach cramps but this upper one frightened me. So wondering if it is all connected to the really severe pain I had yesterday.