t know this for a fact, but I would be willing to bet that Suboxone would override
Tramadol, resulting in no real effect from
Tramadol. Both
Suboxone and Tramadol are active at the mu receptor on the brain. Since Suboxone has a very high affinity for this receptor, it would already have the receptor full and I doubt that Tramadol would kick it out. The chances of going into withdrawal are very high. My advice would be not to mix the two, but check with your doctor before you make a decision.