Some meds can
have very dangerous interaction
s with cocaine-- MAOI's in particular would be a horrible mix, and would likely cause a stroke or fatal arrhythmia. The modern antidepressants are not as bad in combination
with cocaine as are the older medication
s like nortriptyline. The problems are not so much the lack of feeling as they are related to potentiation
of cocaine by meds that affect seroton
in and norepinephrine-- namely the antidepressants.